The clinical value is the core factor for determining the products of Chinese patent medicines on the market. It is clear that defining the clinical positioning of Chinese patent medicines and maximizing their clinical efficacy and value are of great practical significance for each Chinese patent medicine. Precise clinical positioning not only requires systematic analysis and summarization of existing literature and clinical practice data

but also requires verification and proof from detailed experimental data

thus to provide scientific support for basic research. In this research

a three-dimensional integration strategy of " traditional Chinese medicine (TCM) theory-clinical practice-basic research" was proposed to play a vital role in clinical positioning and evaluation of Chinese patent medicines. Yixinshu capsule was taken as an example to discuss clinical positioning of Chinese patent medicines under the guidance of TCM theory. Based on the interpretation of the evolution of the pathogenesis of coronary heart disease (thoracic obstruction)

combined with the core efficacy of the drug composition

the effect of Yixinshu capsule in benefiting Zongqi

calming midnd

improving blood circulation and eliminating blood stasis was identified

which was suitable for treatment for the recurrent episodes of angina pectoris

and emergency of symptoms of chronic heart failure. At the level of TCM theory

the clinical positioning of Yixinshu capsule was further defined

and the key points of in-depth research were proposed to provide reference for the mechanism research and clinical application of Yixinshu capsule. Based on the prescription and its score functions

precise analysis of clinical positioning of large varieties of TCM under the guidance of TCM theory

on the one hand will give full play to the value of TCM original knowledge and guide the basic research of Chinese patent medicines

on the other hand the research results will enrich

benefit and sublimate the TCM theory

and finally provide a critical paradigmatic for the clinical positioning of large varieties of TCM under the guidance of TCM theory.