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1.北京中医药大学,北京 100029;
2.国家中医药管理局 名医名方重点研究室,北京 100029
吴梦婷,在读硕士,从事中医药治疗生殖疾病的机制研究,E-mail:476494609@qq.com
苏泽琦,博士,助理研究员,从事中西医结合基础与临床研究,E-mail:suzeqi@aliyun.com
收稿日期:2019-03-05,
网络出版日期:2019-05-16,
纸质出版日期:2019-10-20
移动端阅览
吴梦婷, 王停, 刘珊, 等. 基于名医名家临证经验的前列腺增生症中医证候、证素分布文献分析[J]. 中国实验方剂学杂志, 2019,25(20):173-180.
Meng-ting WU, Ting WANG, Shan LIU, et al. Literatures on Distribution Features of Traditional Chinese Medicine Syndromes and Syndrome Elements of Benign Prostatic Hyperplasia Based on Experience of Famous Doctors[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(20): 173-180.
吴梦婷, 王停, 刘珊, 等. 基于名医名家临证经验的前列腺增生症中医证候、证素分布文献分析[J]. 中国实验方剂学杂志, 2019,25(20):173-180. DOI: 10.13422/j.cnki.syfjx.20191724.
Meng-ting WU, Ting WANG, Shan LIU, et al. Literatures on Distribution Features of Traditional Chinese Medicine Syndromes and Syndrome Elements of Benign Prostatic Hyperplasia Based on Experience of Famous Doctors[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(20): 173-180. DOI: 10.13422/j.cnki.syfjx.20191724.
目的:
2
基于名医名家临证经验,明确前列腺增生症(BPH)证候类型及证候要素分布规律,以期为指导临床实践及科学研究提供依据。
方法:
2
确定名医名家名单,系统检索1997年1月1日至2018年12月31日,中国知网(CNKI),中国生物医学文献服务系统(CBM)、重庆维普中文期刊数据库(QVIP)、万方数据库中名医名家诊治BPH相关文献,根据纳入标准及排除标准,对检索的相关文献阅读后,纳入合格文献。建立文献分析数据库,分析、整合中医证候及证候要素相关内容,应用SPSS 20.0软件进行统计,获得BPH中医证候类型及证候要素分布特点。
结果:
2
该研究共纳入合格文献141篇,涉及92位名医名家,结合医家对BPH整体论述及医案列举,得到BPH常见证候类型为肾虚血瘀证、膀胱湿热证、肾阴虚证、肾阳虚证、肝郁气滞证等;病位证素主要为肾、膀胱、脾、肺、肝;病性证素主要为血瘀、气虚、热、阳虚、湿等。对医案中症状特点进行归纳整理,得到BPH常见症状为尿频、尿滴沥、尿急、夜尿增多、排尿困难等;舌质以淡红、红、暗红、瘀斑瘀点为主;舌苔以黄腻、薄白、薄黄、白腻为主;脉象以沉细、细涩、弦脉、弦滑为主。
结论:
2
该研究基于名医名家临证经验,得出BPH病位在下焦,主要责之肾与膀胱,核心病机总属本虚标实,肾虚为本,瘀血、湿热、痰浊、气滞为标,且以复合证型多见。
Objective:
2
Based on the experience of famous doctors
the pattern of syndromes of benign prostatic hyperplasia (BPH) and the distribution of syndrome elements are defined to provide a basis for guiding clinical practice and scientific research.
Method:
2
The name list of famous doctors was defined. Relevant literatures on famous doctors' diagnosis and treatment of BPH between January 1
1997 and December 31
2018
were systematically retrieved in CNKI
CBM
CQVIP
Wanfang database. According to the inclusion criteria and exclusion criteria
relevant literatures were read
and eligible literatures were included. A literature analysis database was established for analysis and integration of relevant content of traditional Chinese medicine(TCM) syndromes and syndrome elements. SPSS 20.0 software was used for statistics and analysis of BPH TCM syndrome types and distribution characteristics of syndrome elements.
Result:
2
This study included a total of 141 eligible documents
involving 92 famous doctors. Based on the doctors' overall discussion of BPH and medical case examples
common types of BPH syndrome included kidney deficiency and blood stasis syndrome
bladder dampness syndrome
kidney Yin deficiency syndrome
kidney Yang deficiency Syndrome
liver Qi stagnation syndrome
main symptom factors of disease location included kidney
bladder
spleen
lung
liver
and main symptom factors of disease nature included blood stasis
Qi deficiency
heat
yang deficiency
and dampness. The characteristics of the symptoms in the medical case were collected and summarized
including frequent urinary symptoms
frequent urination
urinary drip
urgency
nocturia
difficulty in urinating
the tongue is mainly light red
red
dark red
and sputum
the tongue coating is mainly yellow
thin white
thin yellow and white greasy
and the pulse is mainly composed of deep
fine
string and slipping.
Conclusion:
2
Based on the experience of famous doctors
the core pathogenesis of BPH is deficient in origin and excessive in superficiality
the kidney deficiency is the root cause
the dampness heat is the symptom
and the compound syndrome is common.
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