Objective:

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Define traditional Chinese medicine (TCM) therapeutic principles and methods and common prescriptions of benign prostatic hyperplasia (BPH) based on clinical experience of famous doctors.

Method:

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China National Knowledge Infrastructure

China Biology Medicine disc

China Science and Technology Journal Database

Wanfang database were systematically retrieved for literatures of famous doctors in diagnosis and treatment of BPH from January 1

1997 to December 31

2018.A literature analysis database was established for integration and analysis of relevant content of TCM therapeutic principles and methods and prescriptions. SPSS 20.0 software was used for statistics to obtain TCM therapeutic principles and methods

common prescriptions and drug distribution regularity of BPH.

Result:

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A total of 109 qualified literatures were included in this study

involving 66 famous doctors and experts

and 9 kinds of BPH therapeutic principles were obtained

including " treatment of both symptoms and root cause of disease"

" tonification and purgation in combination"

" coordination of Yin and Yang" . There are 55 kinds of therapies

including " promoting blood circulation for removing blood stasis"

" clearing heat and promoting dampness"

" warming and recuperating kidney Yang"

" softening and resolving hard mass" and " invigorating kidney Qi" . And BPH was mostly diagnosed and treated based on kidney

spleen and lung. Through collection and summarization

totally 38 formulas commonly used in treating BPH obtained. The most commonly used ones were " Guizhi Fuling Wan"

" Zishen Tongguan Wan"

" Buzhong Yiqi Tang"

" Bazheng Tang" and " Jisheng Shenqi Wan" . There were 217 commonly used herbs

mainly including " Astragali Radix"

" Rehmanniae Radix Praeparata"

" Atractylodis Macrocephalae Rhizoma"

" Glycyrrhizae Radix et Rhizoma"

" Angelicae Sinensis Radix"

" Radix Achyranthis Bidentatae"

" Peach Kernel"

" Pangolin Scales"

" Vaccariae Semen"

" Salviae Miltiorrhizae Radix et Rhizoma"

" Poria"

" Rhizoma Alismatis" and " Plantain Seed" .

Conclusion:

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The treatment of BPH is based on the principles of " treatment of both symptoms and root cause of disease

and tonification and purgation in combination" . The commonly used therapies include prescription for " promoting blood circulation for removing blood stasis"

" clearing heat and promoting dampness" and " warming and recuperating kidney Yang" . The corresponding prescriptions shall be based on symptoms.