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中国中医科学院 广安门医院,北京 100053
张振鹏,博士,副主任医师,第六批全国老中医药专家学术经验继承人,从事中西医结合心血管病研究,E-mail:zzpshou@163.com
李军,博士,主任医师,从事中西医结合心血管病研究,Tel:010-88001094,E-mail:doctorli1031@163.com
网络出版日期:2020-06-16,
纸质出版日期:2020-08-20
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张振鹏,邢雁伟,李军等.非ST段抬高型心肌梗死证候分布及其中医药干预策略[J].中国实验方剂学杂志,2020,26(16):108-112.
ZHANG Zhen-peng,XING Yan-wei,LI Jun,et al.Distribution of Non-ST Segment Elevation Myocardial Infarction Syndromes and Traditional Chinese Medicine Intervention Strategies[J].Chinese Journal of Experimental Traditional Medical Formulae,2020,26(16):108-112.
张振鹏,邢雁伟,李军等.非ST段抬高型心肌梗死证候分布及其中医药干预策略[J].中国实验方剂学杂志,2020,26(16):108-112. DOI: 10.13422/j.cnki.syfjx.20201627.
ZHANG Zhen-peng,XING Yan-wei,LI Jun,et al.Distribution of Non-ST Segment Elevation Myocardial Infarction Syndromes and Traditional Chinese Medicine Intervention Strategies[J].Chinese Journal of Experimental Traditional Medical Formulae,2020,26(16):108-112. DOI: 10.13422/j.cnki.syfjx.20201627.
目的
2
分析非ST段抬高型心肌梗死患者的证候特点和分布规律,以期指导临床实践,提高中医药的疗效。
方法
2
选取符合诊断标准的非ST段抬高型心肌梗死住院患者,利用频数统计法分析中医证候要素的频次和常见程度,以及全部证候的分布特点。
结果
2
263例非ST段抬高型心肌梗死患者的中医证候要素的频次和常见程度分析发现,非ST段抬高型心肌梗死病机多为本虚标实,虚实夹杂。其中本虚以气虚(171频次,32.39%)最为常见,其次是阴虚(42频次,7.95%)较为常见,阳虚(16频次,3.03%)和血虚(1频次,0.19%)相对少见;而标实则以血瘀(129频次,24.4%)和痰浊(125频次,23.7%)最为常见,其次是热蕴(42频次,7.95%)较为常见,水饮(2频次,0.38%)相对少见。根据证候要素组合的证候诊断分析,使用单一证候辨证者220例,占83.65%,使用两个证候同时辨证者42例,占15.97%,3个证候同时辨证者1例,占0.38%。单一证候辨证者220例中,中气虚血瘀证(94例,42.7%)最为常见,其次是痰瘀互结证(46例,20.9%),气阴两虚证(41例,18.6%)和心肾亏虚证(32例,14.6%)较为常见,阳虚水泛证(6例,2.73%)及心火炽盛证(1例,0.45%)相对少见。根据证候分布规律,探讨中医治疗方法以补益正气、固护肾气为主,祛痰浊利水湿与活血化瘀并重。
结论
2
非ST段抬高型心肌梗死病机属本虚标志、虚实夹杂,本虚多为气虚、阴虚,标实多为血瘀、痰浊、热蕴。中医治疗多运用益气养阴、活血化瘀、清热化痰等方法。
Objective
2
To analyze the syndrome characteristics and distribution regularity of patients with non-ST segment elevation myocardial infarction (NSTEMI)
in order to guide clinical practice and improve the efficacy of traditional Chinese medicine.
Method
2
Inpatients with non-ST segment elevation myocardial infarction in line with the diagnostic criteria were selected
and the frequency statistics method was used to analyze the syndrome elements and their frequency degree and distribution characteristics.
Result
2
According to the analysis of syndrome elements and their frequency degree of 263 patients with NSTEMI
the pathogenesis of NSTEMI was mostly deficiency in origin and excess in superficiality. As for deficiency in origin
Qi deficiency (171 times
32.39%) was the most common
which was followed by Yin deficiency (42 times
7.95%)
Yang deficiency (16 times
3.03%)
and blood deficiency (1 times
0.19%). As for excess in superficiality
blood stasis (129 frequency
24.4%) and phlegm turbidity (125 frequency
23.7%) were the most common
which were followed by heat accumulation (42 frequency
7.95%)
water drinking (2 frequency
0.38%). According to the syndrome diagnosis analysis of the combination of syndrome elements
220 cases (83.65%) had single syndrome differentiation
42 cases (15.97%) had two syndromes at the same time
and 1 case (0.38%) had three syndromes at the same time. Among all the syndrome types
Qi deficiency and blood stasis syndrome (94 cases
42.7%) was the most common
which were followed by phlegm and blood stasis syndrome (46 cases
20.9%)
Qi and Yin deficiency syndrome (41 cases
18.6%) and heart and kidney deficiency syndrome (32 cases
14.6%). And Yang deficiency and water flooding syndrome (6 cases
2.73%) and heart fire blazing syndrome (1 case
0.45%) were relatively rare. According to the distribution regularity of syndrome
traditional Chinese medicine therapies were mainly for tonifying vital qi and protecting kidney Qi
with equal emphasis on removing phlegm
eliminating dampness and diuresis
activating blood circulation and removing blood stasis.
Conclusion
2
The pathogenesis of NSTEMI is deficiency in origin and excess in superficiality. Deficiency in origin is mostly Qi deficiency and Yin deficiency
while excess in superficiality is mostly blood stasis
phlegm and heat accumulation. traditional Chinese medicine therapies are mostly for invigorating Qi and nourishing Yin
promoting blood circulation and removing blood stasis
clearing heat and resolving phlegm.
中华医学会心血管病学分会 , 中华心血管病杂志编辑委员会 . 非ST段抬高型急性冠状动脉综合征诊断和治疗指南(2016) [J]. 中华心血管病杂志 , 2017 , 45 ( 5 ): 359 - 376 .
葛均波 , 戴宇翔 . 中国非ST段抬高型急性冠状动脉综合征诊断和治疗现状 [J]. 浙江医学 , 2017 , 39 ( 13 ): 1045 - 1047,1052 .
ZHANG Q , ZHAO D , WU X X , et al . Recent trends in hospitalization for acute myocardial infarction in beijing: increasing overall burden and a transition from ST-segment elevation to non-ST-segment elevation myocardial infarction in a population-based study [J]. Medicine , 2016 , 95 ( 5 ): e2677 .
KOOK H Y , JEONG M H , Oh S , et al . Current Trend of acute myocardial infarction in Korea (from the Korea acute myocardial infarction registry from 2006 to 2013) [J]. Am J Cardiol , 2014 , 114 ( 12 ): 1817 - 1822 .
WRIGHT R S , ANDERSON J L , ADAMS C D , et al . 2011 ACCF/AHA Focused Update of the Guidelines for the management of patients with unstable angina/ non-ST-elevation myocardial infarction (updating the 2007 guideline): a report of the American college of cardiology foundation/american heart association task force on practice guidelines [J]. Circulation , 2011 , 123 ( 18 ): 2022 - 2060 .
张俭 , 张敏州 , 郭立恒 , 等 . 中医药治疗急性心肌梗死的系统评价 [J]. 中西医结合心脑血管病杂志 , 2011 , 9 ( 5 ): 513 - 515 .
龙凤玺 , 戴国华 , 赵晨 . 中医药治疗急性心肌梗死临床研究概况 [J]. 辽宁中医药大学学报 , 2014 , 16 ( 5 ): 240 - 242 .
李军 , 王阶 . 冠心病心绞痛证候要素与应证组合的5099例文献病例分析 [J]. 中国中医基础医学杂志 , 2007 , 13 ( 12 ): 926 - 927,930 .
毕颖斐 , 王贤良 , 赵志强 , 等 . 冠心病现代中医证候特征的临床流行病学调查 [J]. 中医杂志 , 2017 , 58 ( 23 ): 2013 - 2019 .
ROSAMOND W , FLEGAL K , FRIDAY G , et al . Heart disease and stroke statistics-2007 update. A report from the american heart association statistics committee and stroke statistics subcommittee [J]. Circulation , 2007 , 115 ( 5 ): e69 - e171 .
ANDERSON J L , ADAMS C D , ANTMAN E M , et al . 2011 ACCF/AHA focused update incorporated into the ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines [J]. Circulation , 2011 , 123 ( 18 ): e426 - e579 .
程龙 . 《中药、天然药物治疗冠心病心绞痛临床研究指导原则》解读 [J]. 中国执业药师 , 2012 , 9 ( 3 ): 3 - 6 .
中华人民共和国卫生部 . 中药新药临床研究指导原则 [M]. 北京 : 中国医药科技出版社 , 2002 : 72 - 73 .
中国中西医结合学会心血管学会 . 冠心病中医辨证标准 [J]. 中西医结合杂志 , 1991 , 11 ( 5 ): 257 - 258 .
陈可冀 , 张敏州 , 霍勇 . 急性心肌梗死中西医结合诊疗专家共识 [J]. 中国中西医结合杂志 , 2014 , 34 ( 4 ): 389 - 395 .
衷敬柏 , 王阶 , 赵宜军 , 等 . 病证结合与方证相应研究 [J]. 辽宁中医杂志 , 2006 , 33 ( 2 ): 137 - 139 .
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