Objective

2

To observe the clinical efficacy of Juanbitang iontophoresis combined with warm acupuncture in treatment of wind cold and blocking collaterals syndrome due to external humeral epicondylitis (EH) and the effect on serum oxidative stress index.

Method

2

From January 2018 to October 2019

180 patients with EH wind cold and blocking collaterals syndrome were randomly divided into the warm acupuncture group

the traditional Chinese medicine（TCM） group and the combination group

with 60 cases in each group. The TCM group was treated with modified Juanbitang combined local iontophoresis at Quchi (affected side)

Zhouliao (affected side)

Ashi (affected side)

30 min/time/day

while the warm acupuncture group was treated with warm acupuncture once a day

5 days/week. The combination group was treated with warm acupuncture in addition to the therapy of the TCM group

and the three groups were treated for 4 weeks. JOA’s elbow joint function scale

HSS’ elbow joint score scale and pain visual simulation score (VAS) were used to evaluate the symptoms and signs and the improvement of daily life before and after treatment. Enzyme linked immunosorbent assay（ELISA） method was used to detect the contents of late oxidized protein products (AOPP)

malondialdehyde (MDA)

superoxide dismutase (SOD) and heme oxygenase-1 (HO-1) in serum of patients before and after treatment. The cure rate

the total effective rate and the recurrence rate of 1 month and 3 months after treatment were compared.

Result

2

Compared with before treatment

JOA and HSS scores increased

whereas VAS scores decreased (

P

<

0.05). AOPP and MDA contents decreased

while SOD and HO-1 contents increased in the combination group and the TCM group (

P

<

0.05). Compared with the TCM group and the warm acupuncture group after treatment

JOA

HSS score and pain R value increased

whereas VAS score decreased (

P

<

0.05). Compared with the warm acupuncture group after treatment

serum AOPP

MDA content decreased

while SOD

HO-1 content increased (

P

<

0.05). After 4 weeks of treatment

the cure rate and the effective rate of combination group were higher than those of the TCM group (

χ

2

cure rate

=4.617

χ

2

effective rate

=6.471

P

<

0.05) and the warming acupuncture group (

χ

2

cure rate

=4.207

χ

2

effective rate

=6.775

P

<

0.05). One month after the treatment

the cure rate and the effective rate of the combination group were higher than those of the TCM group (

χ

2

cure rate

=7.617

χ

2

effective rate

=13.347

P

<

0.05) and the warm acupuncture group (

χ

2

cure rate

=4.762

χ

2

effective rate

=6.277

P

<

0.05). The recurrence rate of the combination group was lower than that of the TCM group (

χ

2

=9.32

P

<

0.05) and the warm acupuncture group (

χ

2

=3.899

P

<

0.05). Three months after the treatment

the cure rate and the effective rate of the combination group were higher than those of the TCM group (

χ

2

cure rate

=4.789

χ

2

effective rate

=9.643

P

<

0.05) and the warm acupuncture group (

χ

2

cure rate

=4.458

χ

2

effective rate

=9.251

P

<

0.05). The recurrence rate of the combination group was lower than that of the TCM group (

χ

2

=4.599

P

<

0.05) and the warm acupuncture group (

χ

2

=4.518

P

<

0.05).

Conclusion

2

Modified Juanbitang and the warm acupuncture has a good clinical efficacy in the treatment of EH wind cold and blocking collaterals syndrome and is worthy of clinical promotion.