Objective

2

To observe the clinical efficacy of Jiwei Huangqi Guizhi Wuwutang combined with Xingnao Kaiqiao acupuncture on shouder-hand syndrome (SHS)

and its effect on neurogenic inflammatory factors and hemorheology.

Method

2

One hundred and forty-eight patients were randomly divided into control group and observation group (74 cases). Both groups' patients got rehabilitation measures

such as diclofenac sodium sustained release tablets for two to four weeks

75 min/time

1 time/day

and patients with apparent swelling got prednisone acetate tablets for one to two weeks

10 min/time

1 time/day. And patients in control group got Xingnao Kaiqiao acupuncture

1 time/day

6 times/week. Control grouporal Naoxintong capsule 4 tablets/time

3 times/day

patients in observation group were added with Jiwei Huangqi Guizhi Wuwutang

1 dose/day. The courses of treatment were 4 weeks. Before and after treatment

shoulder hand syndrome scale (SHSS)

the upperextremities of the Fugl-meyer movement assessment (U-FMA)

ability of daily life activities (ADL)

Qi deficiency and blood stasis syndrome and clinical efficacy were scored

disappearing time of pain and swelling were recorded

and levels of calcitonin gene related peptide (CGRP)

substance P (SP)

bradykinin (BK) and hemorheology were detected.

Result

2

The clinical efficacy in observation group was better than that in control group (

Z

=2.106

P

<

0.05). And scores of sensory

autonomic

motion according to SHSS scale and the total scale of SHSS were all lower than those in control group (

P

<

0.01). Disappearing time of pain and swelling were shorten than those in control group (

P

<

0.01). After treatment

scores of U-FMA and ADL were higher than those in control group (

P

<

0.01)

while score of syndrome of Qi deficiency and blood stasis was lower than that in control group (

P

<

0.01). And level CGRP was higher than that in control group (

P

<

0.01)

and levels of SP and BK were lower than those in control group (

P

<

0.01). After treatment

whole blood viscosity (high cut

low cut)

plasma viscosity

fibrinogen and platelet aggregation rate were all lower than those in control group (

P

<

0.05).

Conclusion

2

In addition to the conventional western medicine therapy

Jiwei Huangqi Guizhi Wuwutang combined with Xingnao Kaiqiao acupuncture can reduce the severity of SHS and clinical syndromes of traditional Chinese medicine

shorten the course of disease

improve the motor function of upper limbs

inhibit the neurogenic inflammatory reaction

and improve the blood flow

the ability of daily life and the clinical efficacy of patients..