LI Lan-ying, WANG Pei-juan, PENG Yun-ru, et al. Effect of Bushen Huoxuetang on Reproductive-endocrine Disorder Induced by Immobilization Stress in Femail Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(10): 144-147.
LI Lan-ying, WANG Pei-juan, PENG Yun-ru, et al. Effect of Bushen Huoxuetang on Reproductive-endocrine Disorder Induced by Immobilization Stress in Femail Rats[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(10): 144-147. DOI: CNKI:11-3495/R.20110321.1134.009.
Objective: To study the effects of Bushen Huoxuetang(BSHXT)in femail rats with Reproductive-endocrine Disorder(RED)induced by immobilization stress. Method :The female rat model of RED was established by repeated immobilization stress. The serum levels of estradiol(E2)
progesterone(P)
follicle stimulating hormone(FSH)and luteiuizing hormone(LH)were measured by radioimmunoassay(RIA)and
inhibin-B(INHB)
follistatin(FS)and activin-a(ACTA)were measured by enzyme-linked immunosorbent assay(ELISA). Result: The serum level of E2 was significantly increased and the serum levels of INHB
FS and ACTA were obviously reduced in femail rat model treated by larger and middle doses of BSHXT(8.0
4.0 g ·kg-1). Conclusion: BSHXT could obviously protect ovarian function of RED induced by immobilization stress in femail rats.