ZHANG Tai-zhen, CHEN Li, LI Min-li, et al. Treatment of Unstable Angina Pectoris by Sodium Tanshinone Ⅱ Combined with Low Molecular Weight Heparin[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(10): 234-236.
ZHANG Tai-zhen, CHEN Li, LI Min-li, et al. Treatment of Unstable Angina Pectoris by Sodium Tanshinone Ⅱ Combined with Low Molecular Weight Heparin[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(10): 234-236. DOI: CNKI:11-3495/R.20110321.1137.015.
Objective: To investigate the clinical efficacy of sodium tanshinone ⅡA combined low molecular weight heparin treatment for unstable angina patients. Method :A controlled study of patients after informed consent
random allocation method
cases were divided into treatment and control group of 60 cases each. The control group was treated by conventional methods
the treatment group on the basis of the control group
the low molecular weight heparin calcium+sodium tanshinone ⅡA was used. Two groups before and after treatment were observed
including ECG
bleeding time
coagulation time
prothrombin time
the efficacy was determined by analyzing and comparing various indicators. Result: ① The ECG comparison:the treatment group had higher efficiency and efficient
the difference was significant(P<0.05);② Clinical comparison of two groups: the effective rate of the treatment group was 88.33%
control group rate was 65.00%
higher efficacy showed in the treatment group
the difference was significant(P<0.05); ③ In the treatment group three indicators of coagulation(bleeding time
coagulation time
prothrombin time) showed no changes before and after treatment
significant changes in the control group
the difference was significant(P<0.05). Conclusion: The effect of conventional treatment plus low molecular weight heparin+sodium tanshinone ⅡA treatment for patients with unstable angina is safe. It is easy to use