ZHANG Guo-song, FENG Chuan-hua, LUO Xiao-jian, et al. Optimization of Extraction Technology for Saikosaponins from Bupleurum[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(12): 17-20.
ZHANG Guo-song, FENG Chuan-hua, LUO Xiao-jian, et al. Optimization of Extraction Technology for Saikosaponins from Bupleurum[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(12): 17-20. DOI: CNKI:11-3495/R.20110420.0933.012.
Objective: To optimize the extraction technology for the saikosaponins from Bupleurum. Method: The extraction technology for the saikosaponins from Bupleurum was optimized by adopting a single factor experiment and an orthogonal experiment with the use of the extraction rate of the saikosaponins from Bupleurum as the assessment index. Result: The optimized extraction technology for the saikosaponins from Bupleurum was as follows: the powder of Bupleurum with a diameter less than 355 μm was subjected to reflux extraction for 2 times with 80% ethanol (regulate pH to 8) at 80 ℃
each extraction lasting 60 min. For each extraction
the solvent to solid ratio was 8. Conclusion: The extraction technology for the saikosaponins from Bupleurum is simple
reliable
repeatable and suitable for production in industry.