To introduce the properties and preparation of the microsponge and review the applications in various drug delivery systems. The related papers were organized

analyzed and reviewed in recent years. The microsponge

which is formed by cross-linked polymers and drugs

could make the drug release slowly in a specific area. Besides

microsponge could improve the drug stability and reduce drug toxicity and increase the drug bioavailability. So it has be widely used in pharmaceutical and cosmetic fields. Although the study and use of the microsponge delivery system is still in its infancy

it is be concerned by more and more people for its unique advantage. Development of new types of release drug delivery systems for the treatment of local disease will have a potential market.