金银花中的化学成分及其药理作用研究进展

吴娇; 王聪; 于海川

doi:10.13422/j.cnki.syfjx.20190408

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金银花中的化学成分及其药理作用研究进展

综述 | 更新时间：2021-02-09

- 金银花中的化学成分及其药理作用研究进展
- Chemical Constituents and Pharmacological Effect of Lonicerae Japonicae Flos
- 中国实验方剂学杂志 2019年25卷第4期页码：225-234
- 作者机构：
  
  1.新乡医学院　药学院，河南　新乡　 453003；
  2.新乡医学院　医学检验学院，河南　新乡　 453003
- 作者简介：
  
  *吴娇，博士，副教授，从事中药药效成分及其作用机制研究，Tel：0373-3831981, E-mail：wujiao@xxmu.edu.cn
- 基金信息：
  
  河南省自然科学基金面上项目(162300410226);河南省高校科技创新人才支持计划项目(17HASTIT047)
- DOI：10.13422/j.cnki.syfjx.20190408
  中图分类号： R2-0;R22;R284;R285.5
- 收稿：2018-07-19，
  
  网络首发：2018-11-06，
  
  纸质出版：2019-02-20
- 稿件说明：
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吴娇, 王聪, 于海川. 金银花中的化学成分及其药理作用研究进展[J]. 中国实验方剂学杂志, 2019,25(4):225-234.

Jiao WU, Cong WANG, Hai-chuan YU. Chemical Constituents and Pharmacological Effect of Lonicerae Japonicae Flos[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2019, 25(4): 225-234.
吴娇, 王聪, 于海川. 金银花中的化学成分及其药理作用研究进展[J]. 中国实验方剂学杂志, 2019,25(4):225-234. DOI： 10.13422/j.cnki.syfjx.20190408.

Jiao WU, Cong WANG, Hai-chuan YU. Chemical Constituents and Pharmacological Effect of Lonicerae Japonicae Flos[J]. Chinese Journal of Experimental Traditional Medical Formulae, 2019, 25(4): 225-234. DOI： 10.13422/j.cnki.syfjx.20190408.

摘要

金银花是一种具有悠久历史的常用中药，具有清热解毒、宣散风热的功效，集中分布于河南、山东、广东等地。金银花的化学成分主要包括有机酸类、黄酮类、环烯醚萜苷类、三萜皂苷类、挥发油类以及其他各种成分。金银花的药理作用主要为抗炎解热，抗肿瘤，抗菌抗病毒，抗衰老抗氧化，降低血糖，保肝，保护肺脏，神经保护作用，增强机体免疫功能以及抗血小板聚集等。因其具有丰富的药理作用，药用价值高，常可与多种其他药物配伍用于多种方剂之中，临床应用广泛，社会需求量大。本文通过查阅近几年金银花的化学成分及其药理作用方面的相关文献，了解到多名学者对其进行研究并从金银花中首次分离得到多种新的化学成分且对金银花的药理作用机制进了详细研究，因此通过整理相关研究结果，对其进行归纳总结，为更多人认识并了解金银花的最新研究进展提供参考，也可为金银花的开发利用提供科学依据。

Abstract

Lonicerae Japonicae Flos is a commonly used traditional Chinese medicine with a long history. It has the functions of detoxification

heat dissipation and heat dissipation

with a high medicinal value. It is mainly distributed in Henan

Shandong

Guangdong and other places. Researches have shown that the chemical constituents of honeysuckle mainly include organic acids

flavonoids

iridoid glycosides

three terpenoid glycosides

three terpenoid glycosides and volatile oils. And the pharmacological effects of honeysuckle are mainly anti-inflammation and antipyretic

anti-tumor

anti-bacteria

anti-virus

anti-aging and anti-oxidation

lowering blood sugar

protecting liver

protecting lung

neuroprotective

enhancing immune function and anti-platelet aggregation. Because of its rich pharmacological effects and high medicinal value

it has been used in a variety of prescriptions

with wide clinical applications and its large social demands. In this paper

we have reviewed the literatures on the chemical constituents and pharmacological effects of honeysuckle in recent years

and learned that many scholars have studied it

isolated a variety of new chemical components from honeysuckle for the first time and studied the pharmacological effects of honeysuckle in detail. In this paper

we reviewed the research progress of chemical constituents and pharmacological effects of Lonicerae Japonicae Flos

providing references for more people to learn related knowledge of honeysuckle and a scientific basis for the development and utilization of Lonicerae Japonicae Flos.

关键词

Keywords

references

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