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Mechanism of Qiju Dihuang Wan in Treatment of Diabetic Retinopathy Based on NLRP3/Caspase-1/GSDMD Signaling Pathway
Updated：2026-09-17
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    • Mechanism of Qiju Dihuang Wan in Treatment of Diabetic Retinopathy Based on NLRP3/Caspase-1/GSDMD Signaling Pathway

    • “Qiju Dihuang Pill may reduce retinal cell scorch induced by high glucose by inhibiting the activation of NLRP3/Caspase-1/GSDMD signaling pathway, suggesting that it has a protective effect on diabetes retinopathy. The research team has explored the protective mechanism of the drug on diabetes retinopathy, opening up a new direction for the study of Chinese medicine in preventing and treating diabetes microvascular complications.”
    • ZHANG Ge , ZHAO Chunlin , PAN Li , ZHANG Ying , CHEN Zehai , ZHANG Siya , FANG Yiming , SHI Wei
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 20, Pages: 11-21(2026)

    • DOI： 10.13422/j.cnki.syfjx.20260565     

      CLC：

    • Revised：2026-04-14 ，

      Accepted：21 May 2026 ，

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Related Author

FANG Yiming
SHI Wei
CHEN Yanxu
LIU Xin
MA Li
XU Jing
WANG Xianmin
LI Hui

Related Institution

Jiangsu Province Hospital of Chinese Medicine，Affiliated Hospital of Nanjing University of Chinese Medicine
Xinjiang Medical University School of Traditional Chinese Medicine（TCM）
Affiliated Hospital of TCM， Xinjiang Medical University
Gansu University of Chinese Medicine
Traditional Chinese Medicine Inheritance and Innovation Center， The Fourth Affiliated Hospital of Xinjiang Medical University