大承气汤对肠源性内毒素血症大鼠心、肝、肾生化功能致损的保护作用

田在善1; 郑治纲2; 李东华1; 沈长虹1; 吴咸中1

您当前的位置：

首页 >

文章列表页 >

大承气汤对肠源性内毒素血症大鼠心、肝、肾生化功能致损的保护作用

更新时间：2024-01-04

- 大承气汤对肠源性内毒素血症大鼠心、肝、肾生化功能致损的保护作用
- Protective Effect of Dachengqi Decoction on Abnormal Biochemial Functions of Heart, Liver and Kidney in Rats with Enterogenous Endotoxemia
- 中国实验方剂学杂志 1996年2卷第5期页码：34-38
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：
  中图分类号： R285
- 纸质出版日期：1996
- 稿件说明：
移动端阅览
田在善1, 郑治纲2, 李东华1, 等. 大承气汤对肠源性内毒素血症大鼠心、肝、肾生化功能致损的保护作用[J]. 中国实验方剂学杂志, 1996,2(5):34-38.

Tian Zaishan, Zheng Zhigang, Li Donghua, et al. Protective Effect of Dachengqi Decoction on Abnormal Biochemial Functions of Heart, Liver and Kidney in Rats with Enterogenous Endotoxemia[J]. Chinese journal of experimental traditional medical formulae, 1996, 2(5): 34-38.
田在善1, 郑治纲2, 李东华1, 等. 大承气汤对肠源性内毒素血症大鼠心、肝、肾生化功能致损的保护作用[J]. 中国实验方剂学杂志, 1996,2(5):34-38. DOI：

Tian Zaishan, Zheng Zhigang, Li Donghua, et al. Protective Effect of Dachengqi Decoction on Abnormal Biochemial Functions of Heart, Liver and Kidney in Rats with Enterogenous Endotoxemia[J]. Chinese journal of experimental traditional medical formulae, 1996, 2(5): 34-38. DOI：

摘要

采用LPS(po)同时5-HT和Pb-Acet(iv)方法对人鼠进行肠源性内毒素血症(EBTM)造模

治疗组同时经口投予大承气汤(DT)。实验结果表明:造模后3h

心、肝、肾生化功能指标即呈异常改变

而给药组呈保护效应

提示DT对大鼠EETM所致脏器功能损害具有保护作用。

Abstract

An enterogenous endotoxemia(EETM) model was induced by LPS(p.o.)together with 5-HT and Pb-Acet(iv) in rats. The animals in the Treatment group were administered orally with Dachengqi Decoction(DT) simultaneously. The results showed that the abnormal indexes associated with the biochemical functions of heart

liver and kidey occurred in nondrugtreated group as a control 3 hours after the model was set up

while the protective effect on those biochemical functions was found in the treatment group with DT

suggesting that DT could protect the biochemical functions of the organs above from injury by EETM in rats.

关键词

Keywords

references

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

暂无数据