补肾调肝敛乳方对泌乳素分泌影响的动物实验研究

陈新; 刘菊芳; 桂耀庭; 张永锋

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补肾调肝敛乳方对泌乳素分泌影响的动物实验研究

更新时间：2024-01-04

- 补肾调肝敛乳方对泌乳素分泌影响的动物实验研究
- Effects of Bushen Tiaogan Lianru Decoction (BTLD) on the Secretion of Prolactine in Experimental Animals
- 中国实验方剂学杂志 1998年4卷第3期页码：30-32
- 作者机构：
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  中图分类号： R-332
- 纸质出版日期：1998
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陈新, 刘菊芳, 桂耀庭, 等. 补肾调肝敛乳方对泌乳素分泌影响的动物实验研究[J]. 中国实验方剂学杂志, 1998,4(3):30-32.

Chen Xin, Liu Jufang, Gui Yaoting, et al. Effects of Bushen Tiaogan Lianru Decoction (BTLD) on the Secretion of Prolactine in Experimental Animals[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(3): 30-32.
陈新, 刘菊芳, 桂耀庭, 等. 补肾调肝敛乳方对泌乳素分泌影响的动物实验研究[J]. 中国实验方剂学杂志, 1998,4(3):30-32. DOI：

Chen Xin, Liu Jufang, Gui Yaoting, et al. Effects of Bushen Tiaogan Lianru Decoction (BTLD) on the Secretion of Prolactine in Experimental Animals[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(3): 30-32. DOI：

摘要

利用体外垂体组织培养技术及灭吐灵诱导HPRL(Hyperprolactinemia

高泌乳素血症)小鼠模型

以溴隐亭为对照

观察敛乳方的作用?结果:敛乳方不仅可以抑制离体垂体PRL(Prolactin

泌乳素)的分泌

还可拮抗灭吐灵导致的小鼠血清PRL升高?子宫减重?受孕率下降及性周期紊乱

上述作用与溴隐亭相似

敛乳方还可促使未成熟雌鼠阴道上皮细胞角化。

Abstract

An in vitro system of pituitary tissue culture and a HPRL(hyperprolactinemia) mice model induced by metoclopramide were used to observe the effects of BTLD.BTLD not only inhibited the PRL(prolactin) secretion by cultured pituitary tissue

but also can antagonize increase of serum PRL

decrease of womb weight and rate of pregnancy

and disorder of sex circle caused by administration of metoclopramide

these actions of BTLD were similar to those of bromocriptine

besides

BTLD could also spur cornification of vaginal epithelium in immature mice.

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