黄芪建中汤和补中益气汤对脾虚模型小鼠免疫调节作用的实验研究

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- 黄芪建中汤和补中益气汤对脾虚模型小鼠免疫调节作用的实验研究
- Experimental Study on the Immunoregulatory Effect of Huangqi Jianzhong Decoction and Buzhong Yiqi Decoction of Spleen-deficiency Model Mice
- 中国实验方剂学杂志 1998年4卷第5期页码：24-27
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  中图分类号： R-332;R285.5
- 纸质出版日期：1998
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万幸, 刘倩娴, 陈妙欢, 等. 黄芪建中汤和补中益气汤对脾虚模型小鼠免疫调节作用的实验研究[J]. 中国实验方剂学杂志, 1998,4(5):24-27.

Wan xing, Liu qianxian, Chen Miaohuan, et al. Experimental Study on the Immunoregulatory Effect of Huangqi Jianzhong Decoction and Buzhong Yiqi Decoction of Spleen-deficiency Model Mice[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(5): 24-27.
万幸, 刘倩娴, 陈妙欢, 等. 黄芪建中汤和补中益气汤对脾虚模型小鼠免疫调节作用的实验研究[J]. 中国实验方剂学杂志, 1998,4(5):24-27. DOI：

Wan xing, Liu qianxian, Chen Miaohuan, et al. Experimental Study on the Immunoregulatory Effect of Huangqi Jianzhong Decoction and Buzhong Yiqi Decoction of Spleen-deficiency Model Mice[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(5): 24-27. DOI：

采用小鼠大黄脾虚模型

用核素掺入法测定IL-2活性?核素标记靶细胞测定NK活性?微量细胞病变法测定IFN-γ水平。结果:脾虚小鼠的免疫指标明显低于正常组;补中益气汤和黄芪建中汤均能使之提高至正常水平

而对正常小鼠免疫指标无明显影响。

Using the model mice with spleen-deficiency syndrome induced by rhubarb

the IL-2 activity was detected by the method of incorporation of tritiated thymidine

NK activity by the method of tritiated thymidine labeled target cells and IFN-γ-titer by the method of micro-cytopathic effects. The NK activity

IL-2 and IFN-γ levels decreased significantly in the spleen-deficiency groups

while those parameters could be improved to normal level by Huangqi Jianzhong Decoction (HJD) and Buzhong Yiqi Decoction (BYD)

there was no significant change in normal groups treated with HJD or BYD.

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