Objective: To observe the clinical efficacy of combined Chinese and western medicine therapy on acute exacerbation of chronic pulmonary heart disease (CPHD). Method: One hundred and eleven cases (CPHD) with acute exacerbation were randomly divided into 56 cases of the observation group and 55 cases of control group (western medicine group). Conventional western medicine treatment combined with Qingjin Huatan decoction and Xuefu decoction Tang was applied to the observation group

one a day orally for 12 days. Cardiac function

pulmonary artery pressure

arterial blood gas analysis

hemorheological parameters and 6 minutes walking distance were observed. Result: The efficacy of the cardiac function in the observation group was 92.85%

better than that (72.72%) in the control group (P<0.05). Pulmonary artery pressure

arterial blood gas analysis and hemorheological parameters in the observation group were improved better than those in the control group (P<0.01).The walking distance within 6 minutes in the observation group was longer than that in the control group (P<0.01). Conclusion: Combined Chinese and western medicine therapy can effectively reduce pulmonary artery pressure

increase 6 minutes walking distance

reduce blood viscosity

improve heart and lung function for patients with CPHD

and eventually improve the clinical outcome.