Objective: To observe the clinical efficacy of sugar-free particle of Rhodobryum giganteum in treatment angina of diabetic patients with coronary heart disease. Method: A randomized double-blind method was used

105 patients were divided into two groups

and respectively treated with Huixin grass sugar-free particles (66 cases in treatment group) and musk heart-protecting pill (36 patients in control group)

the change was observed on angina pain

electrocardiograph(ECG)

stop or reduction rate nitroglycerin. Result: The efficiency of treatment group was 92.4% in curing angina and 89.7% in control group. There was no significant difference between treatment and control groups. Electrocardiogram efficiency in the treatment group was 57.6% and the control group was 43.6%(P<0.05).Reduction rate of nitroglycerin was 83.3% in treatment group and the control group was 79.5%. Conclusion: The sugar-free particle of R. giganteum of angina pectoris has a good effect in treating angina of diabetic patients with coronary heart disease (ECG improved more significantly).