复方黄柏抗炎止痛巴布剂的基质处方优选

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复方黄柏抗炎止痛巴布剂的基质处方优选

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- 复方黄柏抗炎止痛巴布剂的基质处方优选
- Optimization of Matrix Prescription for Compound Huangbai Anti-inflammatory Analgesic Cataplasm
- 中国实验方剂学杂志 2012年18卷第22期页码：56-58
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- 纸质出版日期：2012
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林以宁, 钱方. 复方黄柏抗炎止痛巴布剂的基质处方优选[J]. 中国实验方剂学杂志, 2012,18(22):56-58.

LIN Yi-ning, QIAN Fang. Optimization of Matrix Prescription for Compound Huangbai Anti-inflammatory Analgesic Cataplasm[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(22): 56-58.
林以宁, 钱方. 复方黄柏抗炎止痛巴布剂的基质处方优选[J]. 中国实验方剂学杂志, 2012,18(22):56-58. DOI：

LIN Yi-ning, QIAN Fang. Optimization of Matrix Prescription for Compound Huangbai Anti-inflammatory Analgesic Cataplasm[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(22): 56-58. DOI：

摘要

目的: 优选复方黄柏抗炎止痛巴布剂的基质处方。方法: 以持黏力为指标

选取聚丙烯酸钠、羧甲基纤维素钠、三氯化铝和甘油的用量为考察因素

采用正交设计法优化复方黄柏巴布剂的基质配比。结果: 最佳基质配方为聚丙烯酸钠-羧甲基纤维素钠-三氯化铝-甘油13∶6∶6∶100。结论: 按优选配方制得的复方黄柏抗炎止痛巴布剂具有良好的初黏力、持黏力、皮肤追随性

且基质与复方提取物具有良好的相容性。

Abstract

Objective:To optimize matrix prescription of compound Huangbai anti-inflammatory analgesic cataplasm. Method: With holding adhesive power as index

the amount of sodium polyacrylate

sodium carboxymethyl cellulose

aluminum trichloride and glycerol were chosen as factors

matrix formulation of compound Huangbai anti-inflammatory analgesic cataplasm was optimized by orthogonal design. Result: Optimal matrix formulation of sodium polyacrylate-sodium carboxymethyl cellulose-aluminum trichloride-glycerol was 13∶6∶6∶100. Conclusion: Prepared compound Huangbai anti-inflammatory analgesic cataplasm had good initial adhesive power

holding adhesive power

skin conformability

and showed good compatibility of matrix and compound extract.

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