Objective: To establish high performance capillary electrophoresis(HPCE) method to determine the content of hesperidin in sucking tablets of jinguo. Method: The running buffe consisted of 25 mmol·L-1borax solution(pH 10.0)

applied voltage was 20 kV

injection pressure was 0.5 psi

injection time was 10 s.The chromatogram was detected at 283 nm. The column temperature was 25 ℃. Result: The linear ranges of the hesperidin was 0.023 8-0.142 9 g·L-1(r=0.999 8).Their respective average recovery was 99.57%(RSD 1.03%). Conclusion: The method is simple

sensitive and rapid

it could be used for the quality control of hesperidin in sucking tablets of jinguo.