Objective: To explore the effect of 3 groups of traditional Chinese medical prescription composed by resolving dampnes

reducing fever

warming Yang

promoting blood cirulation according to the different proportion on obesity rats. Method: Obesity rats model was established by feeding high calorie-diet. The selected rats were randomly divided into six groups: normal control

model group

avandia group

resolving dampnes group

reducing fever group

and warming Yang group. Fasting blood glucose of rats were detected during the drug administration on 0 week

4th week and 8th week.After 8 weeks’ drug administration

oral glucose tolerance test(OGTT)

triglyceride(TG)

total Cholesterol(TC) were determined. Result: After 8 weeks treatment

the blood suger of each group are as follow: normal control(5.30±0.38)mmol·L-1

model group(6.82±0.87)mmol·L-1

avandia group(5.92±0.29)mmol·L-1

resolving dampnes

group (5.69±0.36)mmol·L-1

reducing fever

group(5.69±0.26)mmol·L-1

warming Yang

group(5.35±0.35)mmol·L-1

the TC of each group are as follow: normal control(1.07±0.08)mmol·L-1

model group(1.48±0.11)mmol·L-1

avandia group(1.08±0.19)mmol·L-1

resolving dampnes

group (0.98±0.07)mmol·L-1

reducing fever

group (0.94±0.16)mmol·L-1

warming Yang

group(0.95±0.09)mmol·L-1.The 3 groups of traditional Chinese medical prescription could reduce the content of blood sugar(P<0.05)

TG

TC(P<0.05) and improve OGTT in obesity rats. Conclusion: The 3 groups of traditional Chinese medical prescription has therapeutic effects on obesity rats especially the warming Yang group.