Objective: To observe the change of interleukin-6(IL-6) in peripheral blood and improvement of symptomsin the treatment of wind-cold-damp lumber disc herniation(LDH) with heat-sensitive moxibustion therapy and Duhuo Jisheng decoction. Method: The patients were randomized into a 51-case control group treated with Duhuo Jisheng decoction and a 52-case treatment group treated with Duhuo Jisheng decoction and heat-sensitive moxibustion therapy in which some special acupoints (e.g. Zhiyang

Guanyuan

Weizhong etc.) were selected. IL-6 in peripheral blood was tested and symptomatic change was surveyed. Result: Modified MacNabt were used for therapeutic evaluation and it was found that the curative effect of treatment group was better than that in treatment group(P<0.05);after treatment IL-6 in both groups declined(P<0.05)and effectiveness of treatment group was better than thatin control group(P<0.05). Conclusion: The therapeutic effectiveness of combined therapy of heat-sensitive moxibustion and Duhuo Jisheng decoction is significantly better than that of single decoction method

which may have been caused by that moxibustion stimulated heat-sensitive acupoints

and excite meridian transmission

promote movement of meridian Qi

provoke endogenous modulating system and regulate disordered physiochemical process.