Objective: To study on microwave processing technology of Radix Aconite. Method: The content of six kinds of alkaloids and total alkaloids from different microwave processed products of Radix Aconite were determined by HPLC

and used them as index to compare with traditional processing technology

comprehensive evaluated microwave processing technology of Radix Aconite. Result: Optimum microwave process technology was as follows: after treated by moistening

processed 18-20 min under microwave heating with 60%

and the content of total alkaloids was higher than processed with traditional technology

the content of six kinds of single and double type alkaloids met requirements of 2010 "China Pharmacopoeia". Conclusion: This method was simple

feasible and easy to control

it could be used instead of traditional processing technology of Radix Aconiti as a new method.