SU Yu-ke. Preparation and Permeability of Arnebiae Radix Ointment[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 36-38.
SU Yu-ke. Preparation and Permeability of Arnebiae Radix Ointment[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 36-38.DOI:
Objective: To optimize formulation of Arnebiae Radix ointment. Method: An in vitro model of transdermal permeation was established. In vitro penetration rate of Arnebiae Radix ointment was examined by HPLC
permeation curve was fitted to the Higuchi equation. Result: O/W ointment of Arnebiae Radix had the best penetration rate in all the five formulations
average J value was up to 14.797 μg·h-1·cm-2 calculated with shikonin. Besides
its cumulative permeation curve fitted to the Higuchi equation best. Conclusion: Optimize formulation was O/W ointment.