金礞石人工胃液和水溶性浸出物及其主要元素分析

王栋; 刘卉; 王伯涛

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金礞石人工胃液和水溶性浸出物及其主要元素分析

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- 金礞石人工胃液和水溶性浸出物及其主要元素分析
- Analysis of Major Leaching Elements of Lapis Micae Aureum inSimulated Gastric Juice and Water Extract
- 中国实验方剂学杂志 2011年17卷第12期页码：58-61
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- 基金信息：
  
  "十一五"国家科技支撑计划重点项目(2008BAI55B00)
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- 纸质出版日期：2011
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王栋, 刘卉, 王伯涛. 金礞石人工胃液和水溶性浸出物及其主要元素分析[J]. 中国实验方剂学杂志, 2011,17(12):58-61.

WANG Dong, LIU Hui, WANG Bo-tao. Analysis of Major Leaching Elements of Lapis Micae Aureum inSimulated Gastric Juice and Water Extract[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(12): 58-61.
王栋, 刘卉, 王伯涛. 金礞石人工胃液和水溶性浸出物及其主要元素分析[J]. 中国实验方剂学杂志, 2011,17(12):58-61. DOI：

WANG Dong, LIU Hui, WANG Bo-tao. Analysis of Major Leaching Elements of Lapis Micae Aureum inSimulated Gastric Juice and Water Extract[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(12): 58-61. DOI：

摘要

目的: 分析金礞石人工胃液和水溶性浸出物及其主要元素

为金礞石药用有效成分的研究提供参考资料。方法: 对金礞石药材进行人工胃液浸出和水煎煮浸出

测定浸出率

并采用ICP-AES测定浸出液中主要元素含量。结果: 样品的人工胃液浸出率在5%以上

浸出液中主要元素为Ca

其次为Fe

Al;样品水煎煮的浸出率及各元素的浸出量均较低。结论: 金礞石在临床上多用于丸散少见于汤剂是有科学依据的

其药用物质基础可能与Ca

Mg等人工胃液浸出元素有关。

Abstract

Objective: To study the active component of Chinese traditional medicine Lapis Micae Aureum in simulated gastric juice and water extract. Method: Simulated gastric juice and boiled water were used for leaching

and then both of the leaching rates were measured. The major elements of the extracts were determined with ICP-AES. Result: The leaching rate of simulated gastric juice was above 5%

that’s much higher than water leaching rate

which was less than 0.4%. The major leaching elements in extract of simulated gastric juice were Ca and Mg

and also there were some Fe and Al. Conclusion: It is reasonable that Lapis Micae Aureum usually used as pills and powder rather than decoction in clinical. Ca and Mg may relate to its therapeutical effect.

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