WANG Yue-fei, ZHAO Hong-ye, WANG Yu-ge, et al. Effect of Bioconversion Product of Jade Screen Powder on Cellular Immunity in Immunosuppressed Mice[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(14): 176-178.
WANG Yue-fei, ZHAO Hong-ye, WANG Yu-ge, et al. Effect of Bioconversion Product of Jade Screen Powder on Cellular Immunity in Immunosuppressed Mice[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(14): 176-178.DOI:
Objective: To observe the effect of the bioconversion product of jade screen powder on cellular immunity in immunosuppressed mice. Method: The levels of CD4+T
CD8+T
CD4+T/CD8+T were determined by flow cytometry;The content of serum interleukin-2(IL-2) and interferon-γ(IFN-γ) were detected by ELISA. Result : Compared with cyclophosphamide group
the levels of CD4+T
CD8+T
CD4+T/CD8+T improved in experimental group(P<0.01 or P<0.05) and the content of serum IL-2 and IFN-γ improved obviously in experimental group(P<0.01). Conclusion : The bioconversion product of Jade Screen Powder can promote the cell immunity function
through regulating the balance between CD4+T and CD8+T cells and correcting Th1/Th2 drift phenomenon to keep the superiority of Th1.