SHI Yuan, LI Xia, ZHAO Jiang-he, et al. Study on the Effect of Concentrated Mineral Water and Chinese Hebal Compound on Gastrointestinal Function in Mice[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(9): 128-130.
SHI Yuan, LI Xia, ZHAO Jiang-he, et al. Study on the Effect of Concentrated Mineral Water and Chinese Hebal Compound on Gastrointestinal Function in Mice[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(9): 128-130.DOI:
各给药组对小鼠肠运动的促进作用均显著高于空白组( P <0. 01)。 结论 :HYYPSCS显著促进胃肠蠕动且对乙醇致小鼠胃黏膜损伤具有保护作用
其作用机制可能与其抗氧化作用有关。
Abstract
Objective: To investigate the effect of Concentrated Mineral Water and Chinese Hebal Compound (HYYPSCS) on gastrointestinal function in mice. Method: HYYPSCS (7700
3850 and 1925 mg·kg-1) was ig administrated once a day for 5 days. Acute gastric lesion was induced by ethanol in mice. The ulcer index
ulcer inhibition rate
SOD
MDA and the effect of HYYPSCS on intestinal activities was assessed. Result: Compared with ethanol group
HYYPSCS significantly reduced the ulcer index ( P <0.01)
MDA activity ( P <0.01) and SOD activity was significantly increased ( P <0.05). Compared with Normal group
HYYPSCS can significantly excited intestinal propulsive function ( P <0.01). Conclusion: HYYPSCS can excite gastrointestinal peristalsis and has protective effect on the gastric lesion induced by ethanol in mice.