Objective:To investigate the effects of Xiaoyanlidanpian(XLP) on mice model of experimental hepatitis and acute inflammation.Methods:The experimental hepatitis model was established by injection of Propionibacterium acnes and lipopolysaccharide(P.acnes-LPS) via lateral tail vein.Hepatic function was evaluated by assessing Alanine aminotransferase level(ALT) in plasma.The effect of Xiaoyanlidanpian on allergic contact dermatitis (ACD) induced by DNFB was studied in mice to observe its effect on delayed-type-hypersensitivity(DTH).Croton oil and Carrageenan were used as well to observe its effect on acute inflammation.Results: Compared to the model group

Xiaoyanlidanpian can inhibite the activities of ALT in mice plasma.Meanwhile

Xiaoyanlidanpian could ameliorate the ear swelling in ACD model and acute inflammatory model induced by croton oil.It also reduced the thickness of the mice hind paw induced by carrageenan as well.Conclusion:Xiaoyanlidanpian exerted potential effects on experimental hepatitis.Xiaoyanlidanpian also show partial effect on acute inflammation.