SUN Huan, CHEN Guang, LU Fu-er. Introduction of Several Methods to Establish the Induced Animal Models of Diabetes Mellitus[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(2): 65-68.
SUN Huan, CHEN Guang, LU Fu-er. Introduction of Several Methods to Establish the Induced Animal Models of Diabetes Mellitus[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(2): 65-68.DOI:
Objective:To introduce some methods of producing the induced animal models of diabetes mellitus.Methods:The preparation methods and mechanism for the induced animal models of diabetes mellitus are summarized.The advantage and disadvantage of each method are reviewed respectively.Results:The induced animal models of diabetes mellitus currently available could mainly be divided into three categories:chemicla reagent induced model
transgenic model
gene knock-out model
etc.Conclusion:There are many methods in establishing the induced animal models of diabetes mellitus with their own characters individually.The research progress on animal models of diabetes mellitus might facilitate the further exploration on the etiology
pathogenesis and drug therapy of diabetes mellitus.