萸黄连赤石脂禹余粮汤对小鼠蓖麻油性腹泻及胃肠推进运动的影响

闫彦芳; 张壮; 赵可星; 吴爱明; 吕晞滢; 王硕仁

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萸黄连赤石脂禹余粮汤对小鼠蓖麻油性腹泻及胃肠推进运动的影响

更新时间：2024-01-04

- 萸黄连赤石脂禹余粮汤对小鼠蓖麻油性腹泻及胃肠推进运动的影响
- Effects of the Decoction of Yu-huanglian Chi-shizhi and Yu-yuliang on Diarrhea in Mice and on the Activities of Stomach and Intestines
- 中国实验方剂学杂志 2007年13卷第2期页码：58-60
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- 纸质出版日期：2007
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闫彦芳, 张壮, 赵可星, 等. 萸黄连赤石脂禹余粮汤对小鼠蓖麻油性腹泻及胃肠推进运动的影响[J]. 中国实验方剂学杂志, 2007,13(2):58-60.

YAN Yan-fang, ZHANG Zhuang, ZHAO Ke-xing, et al. Effects of the Decoction of Yu-huanglian Chi-shizhi and Yu-yuliang on Diarrhea in Mice and on the Activities of Stomach and Intestines[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(2): 58-60.
闫彦芳, 张壮, 赵可星, 等. 萸黄连赤石脂禹余粮汤对小鼠蓖麻油性腹泻及胃肠推进运动的影响[J]. 中国实验方剂学杂志, 2007,13(2):58-60. DOI：

YAN Yan-fang, ZHANG Zhuang, ZHAO Ke-xing, et al. Effects of the Decoction of Yu-huanglian Chi-shizhi and Yu-yuliang on Diarrhea in Mice and on the Activities of Stomach and Intestines[J]. Chinese journal of experimental traditional medical formulae, 2007, 13(2): 58-60. DOI：

摘要

目的:观察萸黄连赤石脂禹余粮汤抗小鼠实验性腹泻的的作用

并探讨其作用机理。方法:采用蓖麻油引起小鼠腹泻

以思密达为阳性对照药

观察记录给药6h内各时段的腹泻次数;并观察其对小鼠墨汁胃肠推进率的影响。结果:与模型组比较

萸黄连赤石脂禹余粮汤的大、中、小剂量组和思密达组分别在1

4h不同时段的平均腹泻次数显著减少

差异具有显著统计学意义(P<0.05);萸黄连赤石脂禹余粮汤中剂量组的墨汁胃肠推进率明显下降

差异具有显著统计学意义(P<0.05)。结论:萸黄连赤石脂禹余粮汤对小鼠蓖麻油性腹泻具有一定的防治作用

并且其抗腹泻作用与抑制胃肠推进运动有关。

Abstract

Objective:To stuty the effect and mechanism of the decoction of Yu-huanglian Chi-shizhi and Yu-yuliang on diarrhea in mice.Methods:Taking smectite powder as positive controlled medicine

we arose diarrhea of the mice by castor oil

and observed the drug's effect on ink-pushing of the stomach and intestines of the mice.Results:Compared with the untreated group

the average degrees of the diarrhea of the large dose group and middle dose group and the smectite powder group reduced obviously 1

2 and 4hours later.The difference has obvious statistics sense(P<0.05).The ink-pushing rate in the stomach and intestines of the middle dose group of the decoction of Yu-huanglian Chi-shizhi and Yu-yuliang reduced obviously.The difference has obvious statistics sense(P<0.05).Conclusions:The decoction of Yu-huanglian Chi-shizhi and Yu-yuliang has prevention and cure effect on diarrhea in mice induced by castor oil

and its effect of resisting diarrhea relates to restraining the movement of the stomach and intestines.

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