XU Chao-yang, YANG Jie-ren, LIU Xiao-ping, et al. Effects of Danshen Glucose Injection on the Biochemical Indexes in Dogs by Coronary Artery Ligation[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(2): 43-45.
XU Chao-yang, YANG Jie-ren, LIU Xiao-ping, et al. Effects of Danshen Glucose Injection on the Biochemical Indexes in Dogs by Coronary Artery Ligation[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(2): 43-45.DOI:
Objective:To investigate the effects of Danshen glucose injection on the biochemical indexes in dogs coronary artery ligation.Methods:The acute myocardial ischemia model was established in dogs by ligation of coronary artery.The serum concentrations of LDH
CPK
LD
NEFA
SOD、MDA were detected before the administration of Danshen and after 30
45
60
120
180 minutes of administration respectively.Results:Danshen(3.2g/kg
0.8g/kg) can significantly decrease the activity of CPK and LDK
reduce the content of LD
NEFA
MDA and increase the level of SOD.Conclusion:Danshen glucose injection can protect myocardium against the acute ischemia induced injury in dogs.