QIAO Hai-fa, YANG Sheng, ZHOU Wen-xia, et al. Effect of Active Fraction of Tiaoxin Recipe on Long-term Potentiation of CA1 in Rat Hippocampal Slices[J]. Chinese journal of experimental traditional medical formulae, 2005, 11(1): 31-34.
QIAO Hai-fa, YANG Sheng, ZHOU Wen-xia, et al. Effect of Active Fraction of Tiaoxin Recipe on Long-term Potentiation of CA1 in Rat Hippocampal Slices[J]. Chinese journal of experimental traditional medical formulae, 2005, 11(1): 31-34.DOI:
Aim:To investigate the active fraction A(TRX-A) of Tiaoxin Recipe(TXR) on long-term potentiation(LTP) of CA1 area in the rat hippocampl slices.Methods:LTP in CA1 area of rat hippocampal slices
which was induced by high frequency stimulation(100Hz
100pulses)
was recorded with extracellular recording technique.Results:TXR-A or TXR showed no effect on baseline synaptic responses.Compared with the slices pre-incubated and perfused with decoction-free artificial cerebrospinal fluid(ACSF)
population spike(PS) amplitude of slices exposed to TXR-A or TXR ACSF was significantly increased after high frequency stimulation.Conclusion:TXR-A is one of TXR active fractions which facilitate LTP in CA1 area of slices from rat.