养阴益气活血冲剂对培养人脐静脉内皮细胞抗凝和纤溶等功能的影响

万海同1; 白海波2; 杨洁红1; 余道军1; 别晓东2; 蔡宇2; 严伟民2

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养阴益气活血冲剂对培养人脐静脉内皮细胞抗凝和纤溶等功能的影响

更新时间：2024-01-04

- 养阴益气活血冲剂对培养人脐静脉内皮细胞抗凝和纤溶等功能的影响
- The influence of Yin-nourishing Qi-tonifying and Blood-moving Granules on the Anticoagulation and Fabrinolysis by Cultivating endotheliocyte of human umbilical vein
- 中国实验方剂学杂志 2002年8卷第5期页码：24-26
- 作者机构：
- 作者简介：
- 基金信息：
  
  国家自然科学基金资助项目(30070941);浙江省自然科学基金青年科技人才培养专项资助项目(RC00050,301498)
- DOI：
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- 纸质出版日期：2002
- 稿件说明：
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万海同1, 白海波2, 杨洁红1, 等. 养阴益气活血冲剂对培养人脐静脉内皮细胞抗凝和纤溶等功能的影响[J]. 中国实验方剂学杂志, 2002,8(5):24-26.

WAN Hai-tong1, BAI Hai-bo2, YANG Jie-hong1, et al. The influence of Yin-nourishing Qi-tonifying and Blood-moving Granules on the Anticoagulation and Fabrinolysis by Cultivating endotheliocyte of human umbilical vein[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(5): 24-26.
万海同1, 白海波2, 杨洁红1, 等. 养阴益气活血冲剂对培养人脐静脉内皮细胞抗凝和纤溶等功能的影响[J]. 中国实验方剂学杂志, 2002,8(5):24-26. DOI：

WAN Hai-tong1, BAI Hai-bo2, YANG Jie-hong1, et al. The influence of Yin-nourishing Qi-tonifying and Blood-moving Granules on the Anticoagulation and Fabrinolysis by Cultivating endotheliocyte of human umbilical vein[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(5): 24-26. DOI：

摘要

目的:研究养阴与益气活血方药对培养人脐静脉内皮细胞抗凝和纤溶等功能的影响。方法:采用血清药理学方法观察养阴益气活血方药对培养人脐静脉内皮细胞抗凝、纤溶及抗自由基损伤的作用。结果:养阴益气活血方药具有显著增高前列环素(6-keto-PGF1α)含量;提高组织型纤溶酶原激活物(t-PA)的活性

抑制组织型纤溶酶原激活抑制物(PAI)活性的作用;提高超氧化物歧化酶(SOD)活力

降低丙二醛(MDA)含量的作用;降低ET含量

提高NO含量等作用。结论:养阴与益气、活血方药相伍在抗栓、溶栓、抗自由基损伤等方面具有协同作用

认为养阴生津方药是治疗血瘀证的重要法则。

Abstract

To studying the influence of Yin-nourishing Qi-tonifying and blood-moving Granules on the anticoagulation and fabrinolysis by cultivating endotheliocyte of human umbilical vein

obersevation of Yin-nourishing Qi-tonifying and blood-moving recip to the anticoagulation

and fabrinolysis and anti-injury of free radical of cultivating endotheliocyte of human umbilical vein by using the method of serology pharmacology. Yin-nourishing Qi-tonifying and blood-moving recip could obviously increase the content of (6-keto-PGF1α);It could promote the activity of t-PA and inhibit the activity of PAI;It could promote the activity of SOD and decrees the content of MDA;Yin-nourishing recipe could decrease the content of ET and increase the content of NO. The function of the anticoagulation

fabrinolysis and anti-injury of free radical by Yin-nourishing Qi-tonifying and blood-moving recip was much superior than Qi-tonifying and blood-moving recip

with blood-moving recip.

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