Objective: To investigated the Yindan Xinnaotong capsule (YXC) for treatment of diabetes and hyperlipidemia

to provide therapeutic remedy for treating diabetes and hyperlipidemia. Method: Two hundred and twenty patients from Jan 2011 to Jan 2012 were studied

they were divided into two groups randomly. The control was given metformin on the basis of diet control and moderate exercises. The treatment group was received YXC on the basis of the control remedy. The therapeutic course was 8 weeks

the fasting plasma glucose (FPG)

the lipid levels

glycosylated hemoglobin (HbA1c) and the total clinical effect were compared after treatment. Result: FPG

the lipid levels and HbA1c in two groups were significantly improved after treatment (P<0.05). FPG

HbA1c

triglyceride (TG)

total cholestrol (TC) and low density lipoprotein-C (LDL-C) were lower than control

while HDL-C was significant higher (P<0.05). The total clinical effect was 93.6% and 66.4% in treatment group and control group accordingly (P<0.05). Conclusion: The effect of YXC in treatment of diabetes mellitus and hyperlipidemia is remarkable

the blood sugar and lipid levels were improved

more obvious clinical efficient

higher significantly compared with single metformin treatment. It is worth clinical application.