The apigenin widely exist in natural botanicals anticancer drugs

apigenin anti-tumor mechanism has made important progress and breakthroughs

mainly through antioxidant and tumor-associated gene regulation

cell cycle arrest

and inhibition of tumor cell signal transduction pathway

anti-tumor invasion and metastasis

put chemosensitizing chemoprevention ways to play the anti-tumor effect. And anti-tumor mechanism proposed from the autophagy point of in-depth study of apigenin

experimental and clinical significance.