WANG Ai-di, ZHONG Ai-qin, ZHANG Jun-ping. Establishment and Evaluation of Adventitia Damage Induced Atherosclerosis Animal Models[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(14): 239-242.
WANG Ai-di, ZHONG Ai-qin, ZHANG Jun-ping. Establishment and Evaluation of Adventitia Damage Induced Atherosclerosis Animal Models[J]. Chinese journal of experimental traditional medical formulae, 2014, 20(14): 239-242. DOI: 10.13422/j.cnki.syfjx.2014140239.
To review the establishment and evaluation of adventitia damage induced atherosclerosis animal models. Summarized studies of the adventitia damage induced atherosclerosis animal models at home and abroad in recent years. Described the progress of animal species selecting and models establishment and compared the advantages and disadvantages of each model. The common species for this model are rats
mice
rabbits and small pig
etc. Model making method can be divided into adventitia stripping injury
chronic inflammatory stimulation and indirect stimulation. Different models of animal species and production methods have their characteristics
we should choose them according to study needs. Through the introduce in this article
we can provide scientific reference basis for choosing appropriate models of adventitia damage induced atherosclerosis animal models.