Objective: To establish a method for evaluating quality correlation of raw herbs-decoction pieces-extract-dispensing granules of Chaenomelis Fructus from Xuancheng city

and to provide a basis for quality control of dispensing granules in whole process of production. Method: RP-HPLC was employed to determine contents of oleanolic acid and ursolic acid in samples with mobile phase of methanol-water-acetic acid-triethylamine (265 : 35 : 0.1 : 0.05)

detection wavelength at 210 nm and flow rate of 0.6 mL · min-1

their characteristic spectrum were analyzed. Result: Contents of oleanolic acid and ursolic acid in five batches of raw herbs of Chaenomelis Fructus met standard of the 2015 edition of Chinese Pharmacopoeia

which in its decoction pieces

extract and dispensing granules were relatively stable.There was a good correlation among characteristic spectrum of raw herbs

decoction pieces

extract and dispensing granules

there were six common peaks in all characteristic spectrum of them. Conclusion: This method can be used to characterize consistency of active ingredients in raw herbs

decoction pieces

extract and dispensing granules

and to control quality of Xuanmugua dispensing granules in whole process of production.