Objective: To establish the HPLC fingerprint of Yinsangju solid beverage. Method: Ten batches of Yinsangju solid beverage were analyzed by HPLC method on Kromasil C18 column (4.6 mm×250 mm

5 μm) with acetonitrile-0.4% phosphoric acid solution as the mobile phase for gradient elution. The detection wavelength was 268 nm; flow rate was 1.0 mL·min-1; column temperature was 35℃ and the injection volume was 10 μL. The Similarity Evaluation System for Chromatographic Fingerprint of Traditional Chinese Medicine(version 2.0) was used to identify common peaks and evaluate similarity. Result: The HPLC fingerprint of Yinsangju solid beverage was established. Twenty common peaks were identified with similarity of more than 0.9 for 10 batches of samples. Three peaks were identified as chlorogenic acid

liquiritin

and luteolin glycosides. Conclusion: This reliable

available and quick method can be used in the quality evaluation of Yinsangju solid beverage.