Lespedeza cuneata

a kind of plant of Leguminosae family

is widely distributed in northeast China

Shandong

Jiangsu

Zhejiang

Jiangxi

Hubei

Hunan

Sichuan

Yunnan

Fujian

Guangdong

Guangxi and Guizhou in China

with rich resources. This plant has a long medication history in China

and it is commonly used in the aerial parts with the function of heat-clearing and detoxifying

nourishing liver and kidney

benefiting lung

and scattering stasis and detumescence. By accessing CNKI

Wanfang date

SciFinder

PubMed

ScienceDirect

and multiple domestic and foreign databases

recent literature on chemical constituents

biological activity and clinical application L. cuneata were collected and summarized into a review. According to relevant domestic and foreign literature

65 compounds have been isolated from L. cuneata

including 25 flavonoids

12 phenolic acids

8 lignans

4 monosaccharides

and 16 other chemical constituents. Modern pharmacological research showed that L. cuneata and its chemical constituents showed diverse biological activities

such as hepatoprotective

antibacterial

anti-inflammatory

antioxidant

and nyctinastic leaf-movement effects. Particularly

flavonoids had a strong pharmacological activity. In addition

L. cuneata has been widely used as a folk medicine to treat diabetes

hematuria

insomnia

infantile malnutrition and other diseases. Based on the domestic and foreign studies on L. cuneata

the recent progress in the research on chemical constituents

biological activities and clinical applications of this plant was reviewed in this paper to provide reference for the further development and comprehensive utilization of L. cuneata medicinal resources.