Objective:

2

To explore the receiuer operating characteristic(ROC) curve mathematical statistics method to establish the content limit of isoflavones glucoside contents in Astragali Radix

in order to distinguish the difference in isoflavones glucoside content between Hengshan wild-simulated Astragali Radix in Shanxi and cultivated Astragali Radix in Gansu.

Method:

2

A total of 225 samples of 45 batches of wild-simulated Astragali Radix in Hengshan and 210 samples of 42 batches of cultivated Astragali Radix in Gansu were selected as research objects

and isoflavones glucoside contents of these samples were determined by using the method in the edition 2015

Chinese Pharmacopoeia

. Data was statistically analyzed

and the ROC curve was used to determine the critical value of wild-simulated Astragali Radix in Hengshan and transplanted Astragali Radix in Gansu.

Result:

2

The average contents of isoflavones glucoside in imitative wild Astragali Radix in Henshan and cultivated Astragali Radix in Gansu were 0.107%and 0.039%respectively

with statistically significant differences(

P

<

0.01). The ROC curve had a critical value of 0.069%

and its sensitivity and specificity was 100%and 93.33%

and its model diagnostic accuracy was 0.978

which indicated accurate prediction results.

Conclusion:

2

ROC curve can be used to distinguish the critical value of the wild-simulated Astragali Radix in Hengshan and cultivated Astragali Radix in Gansu. The results reflected the regularity of " high quality and good price" in the market. The research provided a theoretical basis for the establishment of standard of high-quality Chinese herbal medicines.