ZHENG Juan, ZHAO Ying, WANG Li-fan, et al. Effect and Mechanism of Saponin on Leydig Cells[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(22): 145-148.
ZHENG Juan, ZHAO Ying, WANG Li-fan, et al. Effect and Mechanism of Saponin on Leydig Cells[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(22): 145-148. DOI: CNKI:11-3495/R.20110920.1432.015.
Objective: To study effects of Codonpsis thalictrifolia on leydig cells. Method: Leydig cells were collected and cultured in vitro with different concentration of saponin to test quantity of testerone and cAMP and MTT absorbance. Result: When saponin concentration was 0.4 g·L-1
quantity of testerone was significantly increased(P<0.05)
content of cAMP was significantly increased(P<0.01)
and MTT absorbance was significantly reduced(P<0.01). Conclusion: The saponin of C. thalictrifolia can strengthen the capability of single leydig cell to secrete testerone