最新刊期
      卷 7 ， 期 4 ， 2001
      • MAO Ping1,MAO Quan-ming1,MA Fu-liang1,WU Yun-ming2,ZHANG Jun1
        Vol. 7, Issue 4, Pages: 1-4(2001)
        摘要：Objective:To Study the optimal extracting techniques of Ruyi-jinhuang plaster.Methods:By using of contents of berberine and minimal lihibitory concentration as indexes,the conditions of extracting volatile oil,alcoholic concentration and extracting time were determined with orthogonal design method.Results:The optimal extracting conditions are as follows:using 90% alcohol as extracting solvent to extract for two times,the first times for 2 hous and second times for 1 hour.Conclusion:The optimal technique is stable and high efficient.  
        关键词：Ruyi-jinhuang plaster;orthogonal design test;berberine;minimal inhibitory concentration   
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        发布时间：2024-01-04
      • TAN Xiao-mei,DAI Kai-jin,LIU Huan-huam,LUO Jia-bo
        Vol. 7, Issue 4, Pages: 4-5(2001)
        摘要：The quantitative method of baicalin in gegen-qinlian pill was reported.The HPLC conditions as follows:C18 Column(250×4mm,10μm),in room temperature,CH3OH∶0.2%H3PO4=48∶52 as mobile phase,flow rate in 1.0ml/min,detected wave length at 280nm,and the number of theoretical plates calculated by baicalin peak was not less than 3000.The average recovery and relative standard deviation were 100.8% and 1.075%(n=4),respectively.  
        关键词：HPLC method;gegen-qinlian pill;baicalin   
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        发布时间：2024-01-04
      • HE Xia-qiu,HE Jian-hua,MA Yan-qiong,YANG Lei,LIU Jian-xun,WU Xiao-yang
        Vol. 7, Issue 4, Pages: 6-7(2001)
        摘要：The optimized extracting condition of Xuanfei Qutan Oral Liquid were investigated by determining the dried extract and the content of ephedrine chloride with orthogonal design method.Three factors,water volume,decocting time and extracting times,were considered to effect the extracting efficiency of active component.The reasonable extracting conditions were to decoct for three times with water for 1.5 hour each times,and the total water volume were 25 times corresponding to the herbal weight.The quantitative method of ephedrine chloride was used by TLC-scanning method.  
        关键词：orthogonal design;Xuanfei Qutan Oral liquid;ephedine chloride;TLC-scanning Method   
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        发布时间：2024-01-04
      • LIU Bin,SHI Ren-bin,ZHOU Ying,ZHOU Jian-fang
        Vol. 7, Issue 4, Pages: 8-10(2001)
        摘要：The contents of peimine and peiminine in Beilexin capsule were determined with TLCS. The results showed that the linear range was 1.99μg～9.95μg for peimine and 2.00μg～10.00μg for peiminine, respectively. This method was used to determine peimine and peiminine in Beilexin capsule with recovery of 101.5% and 98.5%, respectively. The contents of peimine and peiminine of three batches of samples were determined with this method.  
        关键词：Beilexin Capsule;peimine;peiminine;TLCS   
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        发布时间：2024-01-04
      • HAN Ling1,CHEN Ke-ji2
        Vol. 7, Issue 4, Pages: 17-20(2001)
        摘要：Objective The protective effects of drug-containing serum of Yi-Xin-Kang capsule, a traditional Chinese medicinal prescription, and the individual drugs of the prescription, Danshen and Shanzha, on H+-ATP ase activity of rat myocardial mitochondria injured by oxygen stress were studied.Method Myocardial mitochondria were incubated with oxygen stress injury system(Fe2+/VitC)for 30 min, and then the activity of H+-ATPase was determined. Results Oxygen stress significantly decreased the activity of H+-ATPase of myocardial mitochondria. Treatment with the drug-containing serum of H303 or the individual drugs of Danshen and Shanzha significantly protected the activities of the enzyme. The significant protective effects were observed in lower doses(100 and 200mg/kg) of H303-treated groups and large doses (600mg/kg)of Dan-Shen or Shan-Zha-treated groups. Conclusion H303-containing serum protects the activity of H+-ATPase, a key-enzyme of myocardial mitochondria respiratory chain, injured by oxygen stress, in which Dan-Shen and Shan-Zha may contribute to the effect of H303.  
        关键词：Oxygen stress;Yi-Xin-Kang capsule;drug-containing serum;myocardial mitochondria;H+-ATPase   
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        发布时间：2024-01-04
      • QIN Cai-ling,LIU Ting,Zhang Yi,SUN Yu-ru,SUN You-fu,JIANG Ting-liang
        Vol. 7, Issue 4, Pages: 20-23(2001)
        摘要：Experimental studies Guizhi Tang on rat blood pressure of by non-invasive method demonstrated that Guizhi Tang had significant blood pressure decreasing effect for SHR. Guizhitang had obvious blood pressure increasing effect to Tabellae Reserpini Compsitae-induced low blood pressure rat. Experiment demonstrated that Guizhi Tang had significant dual-directional regulation on blood pressure for rat. Active fractions A(Fr.A) and E (Fr.E),isolated from Guizhi Tang had obvious blood pressure fall in SHR. Active fractions B(Fr.B),isolated from Guizhi Tang had obvious blood pressure rise for Tabellae Reserpini Compsitae-induced low blood pressure rat; The results show that Fr.A and Fr.E and Fr.B are active fractions of Guizhi Tang with dual-directional regulation on rat blood pressure.  
        关键词：Guizhitang;dual-directional regulation;blood pressure;active fractions;SHR   
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        发布时间：2024-01-04
      • Wang Ping,ZHANG Liu-tong,SHI Xue-min,QIU Xing-fang,LIU Ling
        Vol. 7, Issue 4, Pages: 24-27(2001)
        摘要：Objection:to explore the centre mechanism that Xinnao Yizhi prescription improve the function of brain. Methods:to use high performance liquid chromatography to observe the change of 8 amino acids of SAM-P/10's brain,which has close relation with learning memory. Results:preventive prescription and prescription No.Ⅰ drpoed the level of abnormal increased r-GABA obviously (P<0.01 or 0.05),so did western medicine (P<0.05),prescription No.Ⅱ had no obvious effect. Preventive prescription incrased the level of Tau in cortex significantly (P<0.01),so did prescription No.Ⅰ (P<0.05),prescription No.Ⅱ and western medicine only had increasing tendency. Conclusion:Prescription No.Ⅰ that reinforces kidney,resolves phlegm,and restores a clear head regulates abnormal increased EAAs obviously,which is better than that of prescription No.Ⅱ that reinforces kidney,remove stasis.Preventive prescription has the best effect and is better than western medicine. Preventive prescription that drop the level of r-GABA and reduce the level of Tau has the best effect. It prompts that Xinnao Yizhi prescription can regulated the level os SAM-P/10's EAAs and IAAs obviously,This provide bases for the clinical use of Xinnao Yizhi prescription on the encephalic senility and senile dementia.  
          
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        发布时间：2024-01-04
      • LI Bin,LI Lin,YE Cui-fei,LI Zong-xin,ZHENG Jin-lan,CHU Jin,AN Wen-lin
        Vol. 7, Issue 4, Pages: 27-28(2001)
        摘要：To investigate the effect of traditional Chinese compound prescription 962 on serum testosterone (TES),estradiol (E2),triiodothyronine (T3) and tetraiodothyronine(T4) in aged male rats. Results show traditional Chinese compound prescription 962 significantly increased the serum TES concentration and TES/E2 ratio (P<0.05). So traditional Chinese compound prescription 962 Capsule may invigorate the kidney and replenish vital essence,postpone senility,and so improve the learning and memory ability of brain.  
        关键词：Traditional Chinese compound prescription 962;hormones;Postpone senility   
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        发布时间：2024-01-04
      • Vol. 7, Issue 4, Pages: 29-30(2001)
        摘要：Pharmacokinetics in vivo for TTS of total alkaloids of Sophora Flavecens Ait. was studied with Wistar rat and the pharmacokinetics parameters were computed. The rsult showes that it is a kind of 2-compartment model with 1st order absorption.Tp is 8.44hrs,Cm is 6.559ug/ml,t1/2α is 5.679hrs,t1/2β is 19.572hrs and t1/2Ka is 2.83hrs.  
          
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        发布时间：2024-01-04
      • QUAN Shi-jian,XIONG Man-qi,CHEN Rui-chun
        Vol. 7, Issue 4, Pages: 44-46(2001)
        摘要：The model of glomerulonephritis was induced by monoclonal anti-Thy-1 antibodies.The level of IL-1β,TNF-α、IL-6,IL-6 mRNA expression was significantly was significantly incresed than the normal group. Those levels were significantly decresed when Grifola Umbellata decoction or heparin was administered.  
        关键词：Grifola Umbellata Decoction;Thy-1 Nephritis;cytokines   
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        发布时间：2024-01-04
      • WANG Xiao-juan1,WANG Yan-juan1,GUO Jian-sheng2
        Vol. 7, Issue 4, Pages: 47-49(2001)
        摘要：Mieyou Decoction has good effect on treating Superficial Gestritis due to damp-heat in the spleen and the stomach complicated with HP infection, and eliminating HP or preventing recurrence of HP infection.  
        关键词：Mieyou Decoction;helicobacter pylori;Superficial Gastritis;Damp-heat in the spleen and the stomach   
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        发布时间：2024-01-04
      • YANG Ding-you1,DUAN Xue-zhong1,ZHOU Ci-qing2
        Vol. 7, Issue 4, Pages: 50-51(2001)
        摘要：To discuss the influence of Shu Xin Yi Mai Capsule(SXYMC)on α-Granule Membrane Protein-140(GMP-140)in plasma of the Unstable Angina patients(UAP)and to observe the clinical effect,before and after the treatment,plasma GMP-140 was compared with ELISA.At the same time,the symptoms of angina and the change of myocardial ischemia were observed,compared with another 44 cases group of the health.Results showed the level of GMP-140 of teh two groups was higher than the health one(P<0.05).The symptoms of angina and the change of myocardial ischemia were markedly improved in compare with the control one.  
        关键词：Unstable Angina;Shu Xin Yi Mai Capsule;α-Granule Membrane Protein-140   
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        发布时间：2024-01-04
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