最新刊期
卷 ， 期 8 ， 2008
- 摘要：目的:探讨能全面地反映大黄中所含化学成分的指纹图谱的最适进样量。方法:采用HPLC法,系统的适应性条件:色谱柱为Alltech Apollo C18柱;流动相为乙腈-水-1%冰醋酸,梯度洗脱;检测波长为254nm;柱温为40℃。结果:从（22.41～276.24μg）（以大黄酸计算）分别进样,当仅以总信息熵作为参考时,其进样量为276.24μg时的信息熵最大,为3.293×1010,因此确定此条件下大黄指纹图谱的最佳进样量为276.24μg;但若以单位进样量的信息熵比较,那么以61.35μg的图谱所带的信息量最大,为3.354×109。因此确定此条件下大黄指纹图谱的最佳进样量为61.35μg。结论:信息熵可用来确定中药材指纹图谱的最佳进样量。关键词：大黄;指纹图谱;信息熵;进样量;高效液相
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发布时间：2024-09-23 - 摘要：目的:建立HPLC测定郭氏马钱汤中士的宁和马钱子碱的含量测定方法。方法:采用Kromasil-C18（4.6mm×250mm,5μm）色谱柱;流动相为乙腈-0.01mol.L-1庚烷磺酸钠与0.02mol.L-1磷酸二氢钾等量混合溶液（用10%的磷酸调pH值2.8）（19:81）;检测波长为260nm;柱温35℃。结果:士的宁和马钱子碱的进样量分别在（0.46～5.98）μg,（0.20～4.00）μg与其色谱峰面积呈良好线性关系,平均加样回收率分别为100.3%,101.3%。结论:本法简单、准确,可用于郭氏马钱汤中士的宁和马钱子碱的质量控制。关键词：郭氏马钱汤;士的宁;马钱子碱;高效液相色谱法
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发布时间：2024-09-23 - 摘要：目的:为应用桑叶、茶叶、枸杞叶提取多糖及开发相关产品的质量控制提供科学依据。方法:采用苯酚-硫酸法测定不同产地及不同采收时间样品的多糖含量并进行比较。结果:不同产地的桑叶及不同时间采集的枸杞叶其多糖含量有所差异,不同产地绿茶茶叶的多糖含量相差甚小。结论:本方法用于测定桑叶、茶叶、枸杞叶多糖含量,简便、快速、灵敏、重现性好;可根据不同的需要,选择不同产地的桑叶和茶叶提取多糖,在9月份采集枸杞叶可以得到含量较高的多糖。关键词：桑叶;茶叶;枸杞叶;粗多糖;含量分析
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发布时间：2024-09-23 - 摘要：Objective:To develop an HPLC method to determine the contents of both baicalin and wogonin in Tongjing Patch.MethodA Zorbax SB-C18 column（4.6×250 mm,5 μm）was used.The mobile phase was composed of methanol-water-acetic acid（58∶42∶0.05） and the flow rate was 1.0 ml·min-1.UV detection wave length was set at 278 nm.Results:The linear range of baicalin was（0.44～2.20）μg（r= 0.999 7）and the average recovery was 98.64% and the RSD was 1.17%.The linear range of wogonin was（0.012 8 ～ 0.204 8）μg（r= 0.999 9）and the average recovery was 98.96% and the RSD was 2.08%.In three batches of the patches,the contents of baicalin were 7.33%,6.74% and 7.29% and that of wogonin were 0.71%,0.65% and 0.63%.Conclusion:This method is simple and accurate and can be used for the determination of the contents of both baicalin and wogonin in Tongjing Patch.关键词：Tongjing Patch;HPLC;Assay;baicalin;wogonin
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发布时间：2024-09-23 - 摘要：Objective:To study different assaysments of Breviscapinun.Method:Breviscapinun content was assayed both by HPLC and UV,and related digital sequences was compaired through correlation analysis.Result:validation results with the correlating the digital sequences with each other,showed that two methods correlated well with a r= 0.905 5.Conclusion:Two methods correlated well.关键词：breviscapinun;HPLC;UV;the methods of correlation to digital sequences
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发布时间：2024-09-23 - 摘要：目的:建立RP-HPLC法测定复方青骨凝胶中青藤碱的含量。方法:以Waters Xterra RP18（3.9mm×150mm,5.0μm）为色谱柱;甲醇-水-乙二胺（40:60:0.125）为流动相;检测波长:262mm;流速:0.8mL.min-1;柱温:30℃。结果:青藤碱的进样量在（0.215～2.152）μg范围内与峰面积呈良好的线性关系,r=0.9999。平均加样回收率为97.67%,RSD为2.82%（n=6）。结论:该方法简便、快速、准确,可作为复方青骨凝胶中青藤碱的含量测定方法。关键词：复方青骨凝胶;高效液相色谱法;青藤碱;含量测定
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发布时间：2024-09-23 - 摘要：目的:用高效液相色谱法测定妇康片中阿魏酸的含量。方法:采用高效液相色谱法,色谱柱为C18柱（4.6mm×150mm,5μm）,甲醇-1%冰醋酸（28:72）为流动相,流速为1.0mL.min-1,检测波长:323nm;进样量:10μL。结果:阿魏酸在0.05～0.25μg范围内与峰面积呈良好的线性关系,r=0.9999,平均回收率99.76%,RSD=1.08%（n=6）。结论:该方法精密度高,稳定性较好,结果准确可靠,可以用于妇康片的质量检验方法。关键词：妇康片;阿魏酸;高效液相色谱法
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发布时间：2024-09-23 - 摘要：目的:建立清火栀麦片中穿心莲内酯和脱水穿心莲内酯的含量测定方法。方法:以XTerra RP18色谱柱为分离柱,以甲醇-水（45:55）为流动相,采用SPE-HPLC法测定。结果:本品中穿心莲内酯含量测定线性范围为（16.08～160.8）μg.mL-1（r=0.9999）,平均回收率为98.40%（RSD=1.98%,n=6）;脱水穿心莲内酯含量测定线性范围为（8.208～82.08）μg.mL-1（r=0.9999）,平均回收率为97.44%（RSD=1.31%,n=6）。结论:此法操作简单、结果准确,可用于清火栀麦片的质量控制。关键词：清火栀麦片;穿心莲内酯;脱水穿心莲内酯;高效液相色谱法
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发布时间：2024-09-23 - 摘要：目的:建立HPLC测定增智营养片中牛磺酸及盐酸赖氨酸的含量。方法:用2,4-二硝基氟苯柱前衍生化,采用Inertsil C18色谱柱,乙腈-磷酸盐缓冲溶液（19:81）为流动相,检测波长360nm进行测定。结果:牛磺酸及盐酸赖氨酸的线性范围分别为（0.005～0.05）mg.mL-1,r=0.9999,（0.01～0.1）mg.mL-1,r=0.9998,平均回收率分别为99.1%和98.6%,RSD值分别为2.14%和2.06%。结论:该方法操作相对简单,专属性强,重复性好,准确性高,可用于本品的质量控制。关键词：增智营养片;牛磺酸;盐酸赖氨酸;高效液相法
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发布时间：2024-09-23 - 摘要：目的:考察高温、高湿对黄芩、牡丹皮中有效成分含量的影响。方法:将黄芩、牡丹皮药粉分别在高温、高湿条件下放置5d,采用高效液相色谱法测定其有效成分的含量变化。结果:丹皮酚在高温、高湿条件下贮存5d,含量明显降低。黄芩苷在高湿条件下,其含量明显降低;高温情况下,含量反而有所增加。结论:高温、高湿影响中药饮片质量。关键词：高温;高湿;黄芩;牡丹皮
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发布时间：2024-09-23 - 摘要：Objective:To establish a method for the determination of menthol and benzaldehyde in Milian Chuanbei Pipagao by GC with capillary column.Methods:A DB-1 quartz capillary column（0.32 mm×30 m×0.25 μm） was used.The temperature program was as following:the intial temperature of column was kept at 80℃ for 1 min,then raised to 180℃ at the rate of 10℃·min-1,finally to 250℃ at the rate of 25℃· min-1 and maintained the temperature for 5 min.The injection and detection temperature was 220℃ and 260℃.Splitless sampling was used and A FID detector was used.Result:The calibration curves of menthol was obtained with good linear relationship within the range of（3.18～31.8）μg·mL-1（r= 0.999 8）,the recoveries was 98.59%;The calibration curves of benzaldehyde was also obtained with a good linear relationship within the range of（5.25～52.52）μg·mL-1（r= 0.999 9）,the recoveries was 98.27%.Conclusions:This method is simple and accurate,and can be used to control the quality of menthol and benzaldehyde in Milian Chuanbei Pipagao.关键词：Milian Chuanbei Pipagao;Menthol;benzaldehyde;GC;Assay
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发布时间：2024-09-23 - 摘要：目的:对妇炎清泡腾片的处方及制备工艺进行研究。方法:采用正交实验设计,以崩解时间、pH值以及发泡量为指标综合评分筛选处方,对妇炎清的处方进行筛选。结果:最佳处方工艺为A1B1C2,即淀粉与浸膏的比例为2:1、枸橼酸与浸膏的比例为1.5:1g、碳酸氢钠与浸膏的比例为1.25:1。结论:经过优化后的处方制备的妇炎清泡腾片各项指标符合药典规定,工艺重现性好,适于规模化生产。关键词：妇炎清泡腾片;处方;正交设计
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发布时间：2024-09-23 - 摘要：目的:筛选出心衰颗粒合理的提取方法。方法:以总黄酮含量为检测指标,采用正交设计对溶媒用量、提取次数、煎煮时间3个因素进行优选。结果:提取次数（B）、溶媒用量（A）对总黄酮含量有显著性影响;最佳提取工艺为加入药材重量12倍的溶媒,浸泡1.5h,提取3次,每次1h。结论:该工艺方法可行、简便、易于操作。关键词：心衰颗粒;正交设计;总黄酮含量
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发布时间：2024-09-23 -
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- 摘要：Objective:To investigate the anti-tumor effect of Shu-Gan-Liang-Xue（SGLX） decoction from traditional Chinese midicine（TCM） combined with tamoxifen on the graft model of human breast cancer in nude mice and also to analyze the possible mechanism.Methods:The animal model of MCF-7 implanted tumor in nude mice was copied.Mice with implanted tumor were randomly divided into control,tamoxifen（TAM）,SGLX and SGLX+TAM groups.After SGLX decoction was given to mice for 28 days,the inhibitory rate of tumor weight was determined.Cell cycle and cell apoptosis of breast cancer were detected with flow cytometry and TUNEL respectively.The serum estradiol and progesterone were tested by radio-immunity.Results:The inhibitory rate of tumor-weight was 28.30%,26.30%,41.01% respectively in TAM,SGLX and SGLX+TAM groups,with significant difference compared with the control（P<0.01）.Tumor cells in TAM,SGLX and SGLX+TAM groups were blocked at G0/G1 phase.The apoptotic rate was increased obviously in SGLX+TAM group.The serum estradiol was lower in SGLX and SGLX+TAM groups compared with the control at significant level（P< 0.000 1）.Conclusions:SGLX decoction can increase the inhibitory effect of TAM on breast cancer synergetically.The possible mechanism include that SGLX may arrest tumor cells in G0/G1 phase,induce tumor cell apoptosis,and reduce serum estradiol level.关键词：Shu-gan-liang-xue decoction;tamoxifen;breast cancer;nude mice
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发布时间：2024-09-23 - 摘要：Objective:To study the effect of conjugated linoleic acid magnesium selenium（CMS） on body weight reduction in mice fed by high-fat diet.Methods:63 male Kunming mice were randomly divided into five groups,i.e.normal control group 10,model control group 14,low,middle and high dose groups 13 for each,and fed basal diet for the normal control group,fed high-fat diet for others.At the same time,0.2 mL/10g BW 1.5%CMC+CMS aqueous solution were given orally for three dose groups daily,and 0.2 mL/10 g BW 1.5%CMC aqueous solution for the others.After four weeks,body weight,testis fat were weighed,food consumption and serum TG,HDL,CHO,GIU were measured.Results:The body weight were lower significantly for middle dose group（P<0.05） and high dose group（P<0.01）,testis fat weight and index of testis fat weigh/body weight were lower significantly for three dose groups（P<0.01）,food intake consumption had no obvious change compared with the model control.Conclusions:CMS is effective in lowering body weight and body fat in mice fed by high-fat diet.关键词：conjugated linoleic acid magnesium selenium;fat mice;Body weight;body fat;blood fat
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发布时间：2024-09-23 - 摘要：Objective:To investigate the changes of bronchoalveolar lavage fluid（BALF） and peroxidation-induced injury in the long-term smoking model mice,and the effect of Yanqing Tablet on them.Method:The model of long-term smoking of mice was set up.BALF protein concentrations were measured and total leukocytes were counted.Cytospin slides were made and stained to determine the BALF cell differential.The activities of superoxidized dismutase（SOS）,concentrations of malondialdehyde（MDA） and total antioxidative capacity（T-ADC） both in plasma and lung homogenate were detected.Result:Compared with normal control group,in smoking model group,BALF protein concentrations and total leukocytes increased（P<0.05）,the activities of SOD and T-ADC decreased（P<0.05）,concentrations of MDA increased（P<0.05）.While compared with smoking model group,in those groups treated with Yanqing Tablet,BALF protein concentrations dereased（P<0.05）,total leukocytes decreased（P<0.05）,the activities of SOD and T-ADC increased（P<0.01）,concentrations of MDA increased（P<0.05）.Conclusions:There are therapeutic effects of Yanqing tablet on inflammation of air duct and peroxidation-induced injury in the model of long-term smoking of mice.关键词：Yanqing Tablet;bronchoalveolar lavage fluid;superoxidized dismutase;malondialdehyde;total antioxidative capacity
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发布时间：2024-09-23 - 摘要：Objective:To observe the therapeutic effect of Guizhi-Shaoyao-Zhimu（GSZ） decoction on imunologic arthritis and investigate the mechanism of this drug on the disease.Methods:Rats were prepared for immunologic arthritis models induced by Freund’s complete adjuvant（FCA）.Different doses of GSZ decoction（20.6 g·kg-1,10.3 g·kg-1） were administrated on the rat model.The counter-lateral synovial tissues of the knee joint were taken for observing pathological changes and the expression of RANKL.Results:In a 4-week of administration of GSZ,lessened swelling of the joints and arthritis index was observed（P<0.05 or P<0.01）.The pathological findings suggested there was less severe inflammation in synovium of the joints and fibrous tissues and decreased infiltrating cells.The RANKL expression in synovial tissues tended to decrease（P<0.01）.Moreover,the findings suggest that GSZ 20.6 g·kg-1 can be favorable with respect to MTX in treatment of immunologic arthritis.Conclusions:GSZ Decoction can protect the joint impairment of immunologic arthritis rats.The therapeutic mechanism maybe is relevant to inhibit inflammation and the expression of RANKL.关键词：Guizhi-Shaoyao-Zhimu Decoction;immunologic arthritis;receptor activator of NF-κB ligand
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发布时间：2024-09-23 - 摘要：目的:观察心悸宁（XJN）浸膏粉溶液对豚鼠单个心室肌细胞动作电位的影响。方法:使用Langendorff灌流系统离体灌流心脏,急性酶解法分离获得心肌细胞。全细胞膜片钳技术电流钳模式记录动作电位。结果:0.25%XJN使静息电位（RP）从用药前的（-70.62±7.02）mV上升至（-66.99±8.29）mV（P<0.05）,动作电位0相除极幅度（APA）从用药前（114.24±12.30）mV减小至（107.40±13.56）mV（P<0.05）;动作电位0相最大除极速率（Vmax）从用药前（117.49±32.89）V/s减慢至（84.99±25.61）V/s（P<0.01）;复极至50%时动作电位时程（APD50）从用药前（282.94±41.76）ms缩短至（232.10±26.93）ms（P<0.05）;动作电位3相复极速率（V3）从用药前（-3.08±0.69）V/s减慢至（-2.06±1.07）V/s（P<0.05）。0.5%XJN使RP,APA,Vmax和V3的变化与0.25%XJN的变化趋势一致,但APD50和复极至90%时动作电位时程（APD90）延长更显著。结论:体外应用XJN引起心室肌细胞RP上升,APA减小,Vmax和V3减慢。0.25%浓度组引起APD50缩短,0.5%浓度组引起APD50和APD90延长。以上影响可能是XJN在临床上具有广谱抗心律失常作用的电生理学机制。关键词：心悸宁浸膏粉溶液;动作电位;心律失常;膜片钳技术
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发布时间：2024-09-23 - 摘要：Objective:To investigate the effect on angiogensis as well as tumor growth for the traditional Chinese medical astringent,such as,Cortex Ailanthi,and the mechanism of the effect.Method:A model of transplanting tumor in mice was used to study the effect of these medical herbs on tumor growth.The expression of Ⅷ-RAg and matrix metalloproteinase-9（MMP-9） in tumor tissue were examined with immunohistochemical method.The microvessel density（MVD） of the tumour tissue was also measured with the Image Pro Plus software.Result:Cortex Ailanthi could obviously inhibit the growth of sarcoma（S 180） transplanted subcutaneously in mice（P<0.05）.There were fewer vessels in sarcoma tissue in Cortex Ailanthi group than in control group and CTX group（P<0.05）.The expression of MMP-9 was lower in Cortex Ailanthi group than in control group（P<0.05）.Conclusion:Cortex Ailanthi can inhibit angiogensis in tumor tissue,and can also suppress the growth of sarcoma（S 180） transplanted in mice and the expression of MMP-9 in the sarcoma tissue.关键词：Cortex Ailanth;angiogenesis;sarcoma180;MMP-9
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发布时间：2024-09-23 - 摘要：Objective:To study the antiasthmatic,antitussive,and expectorant effects of Suhuangzhike granules.Method:Using the asthma model induced by acetylcholine and histamine mixture,antigen challenging（ovalbumin）and guinea pig’ isolated trachea strip test the antiasthmatic effect was evaluated;using the cough model induced by ammonia,citric acid in mice,the antitussive effect was studied;phenol red test was used to observe the expectorant effect in mice.Result:Suhuangzhike granules could significantly prolong the latent period of twitch of guinea pig caused by acetylcholine and histamine,markedly decrease the number of leucocyte in perfusate of trachea and lung;and the degranulation rate of labrocyte in peritoneal fluid of guinea pig challenged by antigen,significantly decrease the tension of smooth muscle of trachea,significantly prolong the latent period of cough and decrease the frequency of cough induced by citric acid in guinea pig,significantly inhibit the cough induced by ammonia in mice,and increase phenol red excretion of trachea quantity in mice.Conclusion:Suhuangzhike granules has antitussive,antiasthmatic and expectorant actions.关键词：Suhuangzhike Granules;antitussive action;antiasthmatic action;expectorant action
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发布时间：2024-09-23 - 摘要：目的:观察舒筋活络胶囊的镇痛作用和对免疫功能的影响。方法:采用热板法和扭体法考察其对小鼠疼痛的影响;用二硝基氯苯（DNCB）诱导的迟发型超敏反应（DTH）和溶血素测定观察对细胞免疫和体液免疫的影响。结果:舒筋活络胶囊1.66g.kg-1、0.83g.kg-1明显抑制醋酸所致的小鼠疼痛,延长潜伏期;在给药后45,60min能显著提高小鼠痛阈值;能显著抑制DNCB诱导的小鼠DTH反应;能显著抑制小鼠溶血素抗体生成。其1.66g.kg-1对小鼠胸腺生长有抑制作用。结论:舒筋活络胶囊有一定镇痛和抑制免疫功能的作用。关键词：舒筋活络胶囊;镇痛;免疫
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发布时间：2024-09-23 - 摘要：目的:研究顽痹清片的抗炎作用。方法:采用二甲苯致小鼠耳壳肿胀实验、小鼠毛细血管通透性实验、大鼠棉球肉芽肿实验、大鼠佐剂型关节炎实验,观察顽痹清片的抗炎作用。结果:顽痹清片高,中,低剂量各组,均可明显抑制二甲苯所致小鼠耳壳肿胀;高剂量组有明显抑制组胺所致小鼠腹腔毛细血管通透性增加的作用;高,中剂量组对肉芽组织增生及佐剂关节炎模型均有显著抑制作用。结论:顽痹清片有较好的抗炎作用。关键词：顽痹清片;抗炎;佐剂型关节炎
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发布时间：2024-09-23 - 摘要：Objective:Through the anti-fatigue study of the decoction of Shengyang Yiqi to evaluate the therapeutic principle of removing and reinforcing on the anti-fatigue and to offer a new idea for anti-fatigue.Method:Ninety selected male mice（through swimming ability as preliminary screening） were divided randomly into 3 groups.They were blank control group,decotion of raising splen-yang to tonify stomach group,positive control group（spirulina）.The time of burden swimming,the increase of LA after 10 min swimming,the decreases of LA after 15 min rest after swimming,blood urea nitrogen,lactic acid dehydrogenase,hepatic glycogen,muscle glycogen were observed.Results:The results showed that decotion of Shengyang Yiqi could significantly enhance the exercise tolerance of mice,the time of swimming of the decotion group was longer than that of blank control group,the increase of LA after 10 min swimming of this recipe was lower than that of blank control group,the blood urea nitrogen level was also lower than that of blank control group.But this recipe has no effect on hepatic glycogen and muscle glycogen level.Conclusion:The decoction of Shengyang Yiqi has the effectiveness of anti-fatigue and fifteen days of application can demonstrate the anti-fatigue action to mice.关键词：The decotion of Shengyang Yiqi;tradition Chinese medicine;anti-fatigue
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- 400
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发布时间：2024-09-23 - 摘要：Objective:To observe the pharmacological effects of Dieda Niushang Ling Tincture.Methods:Using the model of the adjuvant induced arthritis in rats,the egg white induced paw edema in rats,the cotton cause granulation tissue hyperplasia in rats,the weights collision induced foot traumatic bleeding in mice,hot plate induced pain in mice,to observe the pharmacological role of Dieda Niushang Ling Tincture.Result: The partial use of Diedaniushangling tincture could significantly inhibit the adjuvant induced arthritis in rats,speeded up the absorption of traumatic congestion,had clear anti-inflammatory and analgesic effect.Conclusions:The Dieda Niushang Ling Tincture had the pharmacological effects of antirheumatic,anti-inflammation,promoting blood circulation to remove blood stasis,and analgesia.关键词：Dieda Niushang Ling Tincture;the adjuvant induced arthritis;anti-inflammation;promoting blood circulation to remove blood stasis;analgesia
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- 120
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发布时间：2024-09-23 - 摘要：目的:探讨蜂胶乙醇提取物（EEP）对小鼠肝脏蛋白质与核酸合成代谢的影响。方法:采用放射性同位素标记物3H-Leu、3H-TdR、3H-UR体内掺入的方法,并以液体闪烁计数仪测定3种标记物的掺入量。结果:EEP可提高肝脏内3H-Leu、3H-TdR、3H-UR的掺入量,分别比空白对照组提高了34.64%、55.34%、166.27%,其差别有统计学意义。结论:EEP有促进肝脏蛋白质、DNA、RNA合成的作用。关键词：蜂胶乙醇提取物（EEP）;肝脏;核酸合成;蛋白质合成
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- 114
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发布时间：2024-09-23 -
- 摘要：Objective:To study the composing rule of the similar formulae of Zhizidahuangtang and provid guidance for composing formula of treating jaundice of heat and dampness type.Method:Searching the formulae of previous treating pestilence for the formula of Zhizidahuangtang and its similar formulae,20 formulae talally found were analyzed for each composition herb’s frequency,nature and taste by statistic method for Chinese medicine.Result:（1）There are 42 kind of different herbal drugs used in the similar formulae of Zhizidahuangtang,and among them,Dahuang,Zhizi,Yinchen were most frequently used.（2）Among the compositions of the similar formulae of Zhizidahuangtang,the herbs with cold and cool nature got score of 2.631;the herbs with heat and warm nature got score of 0.257;the rate of cold herbs to heat herbs was about 10∶1.（3） Among the compositions of the similar formulae of Zhizidahuangtang,the herbs with bitter taste was used mostly,herbs with spicy taste were secondly used and sweet ones thirdly.The amount of the three kinds of herbs took 87.2% of all the herbs and 92.2% of all score for the tasle of herbas.The herbs with sour,salty or tasteless taste were far less used.Conclusion:（1） Dahuang,Zhizi,Yinchen are the most common and basic herbs used in treating jaundice of heat and dampness.The formula Yinchenghaotang is the fundamental of treating jaundice of heat and dampness.（2） The formulae of Zhizidahuangtang are mainly composed with cold nature and bitter taste,assisted with a few warm and spicy ones.The together using of using cold and warm,bitter and spicy herbs was not only characterige for formulation of Zhizidahuangtang,but also a formulae rule in treating jaundice of heat and dampness.关键词：Zhizidahuangtang;similar formulae;composing rule;Yinchenghaotang;core-coefficient
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- 325
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发布时间：2024-09-23 -
The Status and Prospect on Studies of the Four Properties for the Traditional Chinese Materia Medica
摘要：Based on the world references in recent ten years and the experiences of the authors,the current status and problems on studies of four properties for traditional Chinese materia medica（TCMM） are analysed.To illustrate the four properties,according to the first law in thermodynamics,biothermodynamics with mathematical status model of enthapy is set up.关键词：TCMM;four properties;thermodynamics;biothermodynamics;enthapy- 0
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- 384
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发布时间：2024-09-23 - 摘要：The progress in the studies of temperature-sensitive,pH-dependent,ion-responsive in situ gels by mucosal drug delivery was reviwed and the applications of in situ gels in all mucosal parts were introduced.Although there were some technical problems remained in situ gel by combining the dosage form of in site gel with the route of mucosal administration,it was a novel drug delivery system with high developing potentials,especially in the study of dosage forms of traditional Chinese medicine.关键词：in situ gel;mucosal drug delivery;drug delivery system
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- 945
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发布时间：2024-09-23 -
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