最新刊期
卷 ， 期 6 ， 2008
- 摘要：Objective:To study the effect of gibberellins and its synthetic inhibitor on tanshinones. Methods: Different concentrations of gibberellins and paclobutrazol were added to the liquid medium, and hairy roots of Salvia miltiorrhiza Bge.were cultivated for 25 days. The concentration of cryptotanshinone, tanshinone Ⅰ and tanshinone ⅡA in the samples were assayed by HPLC. Results: The concentration of cryptotanshinone, tanshinone Ⅰ and tanshinone ⅡA increased in the samples treated with gibberellins, while the concentration of cryptotanshinone, tanshinone Ⅰ and tanshinone ⅡA decreased in the samples treated with paclobutrazol. Conclusions: Paclobutrazol could be synthetic inhibitor of tanshinone ⅡA, and gibberellins can be inducer for production of tanshinones.关键词：Salvia miltiorrhiza Bge.;gibberellins;tanshinones
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发布时间：2024-09-23 - 摘要：目的:建立大方油栝楼药材中葫芦素B的高效液相色谱测定方法。方法:色谱柱为Hypersil C18柱（4.60mm×250mm,5μm）,流动相为甲醇-水（70∶30）,检测波长为227nm。结果:葫芦素B的线性范围为（0.151.81）μg,加样回收率为98.69%。结论:所建立的方法准确、可靠、重复性好,可用于大方油栝楼药材中葫芦素B的含量测定。关键词：大方油栝楼;葫芦素B;高效液相色谱法
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发布时间：2024-09-23 - 摘要：Objective:To develop an HPLC method for the content determination of calycosin-7-0-β-D-glucoside,prim-o-glucosyl cimifugin and 4′-O-β-D-glucosyl-5-O-methylvisammin in Yupingfeng Decoction and related drug pieces,and study the correlation of content in Radix Astragali,Radix Saposhnikovlae and Yupingfeng Decoction. Methods:A Hypersil ODS column was used with acetonitrile-water as a mobile phase（gradient elution） and detecting at 254 nm. The flow rate was 1 mL·min -1 ,and column temperature was 30℃. Results:The extraction percentages of calycosin-7-0-β-D-glucoside in Radix Astragali, prim-o-glucosyl cimifugin and 4′-O-β-D-glucosyl-5-O-methylvisammin in Radix Saposhnikovlae were 45.58%～63.35%,45.01%～65.09%,53.62%～87.75%. Conclusions:There is a correlation between the contents of and Yupingfeng decoctions and related drug pieces, and the different sources of drug pieces cause a variable for extraction percentage,which provides a reference for the material base of Yupingfeng Decoction.关键词：Yupingfeng Decoction;calycosin-7-0-β-D-glucoside;prim-o-glucosyl cimifugin;4′-O-β-D-glucosyl-5-O-methylvisammin;HPLC
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发布时间：2024-09-23 - 摘要：目的:建立胃舒口服液的质量标准。方法:采用薄层色谱法对胃舒口服液中三七、黄芩、陈皮药材进行定性鉴别;采用高效液相法测定芍药苷的含量。色谱柱:Kromasil C18柱（4.6mm×250mm,5μm）;流动相:乙腈-0.1%磷酸溶液（14∶86）;检测波长:230nm;流速:1mL·min-1。结果:芍药苷在0.1760.880μg范围内呈线性关系,r=0.99963,平均回收率为97.47%,RSD=0.89%（n=6）。结论:该方法操作简便,专属性强,重复性良好,结果准确可靠,可作为胃舒口服液的质量控制方法。关键词：胃舒口服液;质量标准;薄层色谱法;高效液相色谱法;芍药苷
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发布时间：2024-09-23 - 摘要：Objective:To develop a RP-HPLC method to determine the contents of protocatechuic acid, protocatechuic aldehyde and tyrosol in Yanlixiao Capsules. Methods: The samples was separated on a YWG C 18 column（4.6 mm×250 mm,10 μm）, using methanol-0.125% glacial acetic acid solution（10∶90）as the mobile phase with flow rate of 1 mL·min -1 and detection at 275 nm. Results:The regression equation of protocatechuic acid was Y= 85 117x -15 733 （r= 0.999 5 ）,and the linear range was at 0.08 μg～0.56 μg. The regression equation of protocatechuic aldehyde was Y= 111 700x -37 980 （r= 0.999 8 ）, and the linear range was at 0.01 μg～0.07 μg. The regression equation of tyrosol was Y= 139 386x -29 146 （r= 0.999 6 ）, and the linear range was at 0.42 μg～2.94 μg. The average recovery of protocatechuic acid was 96.0%, RSD=2.37%（n=6）. The average recovery of protocatechuic aldehyde was 98.4%, RSD=2.05%（n=6）. The average recovery of tyrosol was 97.5%, RSD=1.93%（n=6）. Conclusion: The method is simple,rapid and accurate, and can be used for quality evaluation of Yanlixiao Capsules.关键词：Yanlixiao Capsules;RP-HPLC;protocatechuic acid;protocatechuic aldehyde;tyrosol
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发布时间：2024-09-23 - 摘要：Objective:To develop an HPLC method for determination of ursolic acid in Hawthorn Leaves. Methods:The C 18 column with methanol-water-phosphorous acid （90∶10∶0.03） as the mobile phase was used. The flow rate was 0.5 mL·min -1 and the detection wavelength was 220 nm. Results:The linear range of calibration curve was （0.982～9.82） μg·mL -1 for ursolic acid （r= 0.999 8 ）. The average recovery was 98.16% and the RSD was 0.58% （n=6）. Conclusion:The method is simple, accurate and repeatable. It can be used for the quality control of Hawthorn Leaves.关键词：Hawthorn Leaves;ursolic acid;HPLC;determination
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发布时间：2024-09-23 - 摘要：目的:分析荨麻多糖的单糖组成。方法:采用微晶纤维素薄层板,展开剂系统为正丁醇-乙酸乙酯-吡啶-水（6∶1∶5∶4）下二次展开,苯胺-邻苯二甲酸为显色剂。结果:在正丁醇-乙酸乙酯-吡啶-水（6∶1∶5∶4）展开剂系统下,实现了各单糖组分的分离,荨麻粗多糖主要由鼠李糖、木糖、阿拉伯糖、葡萄糖、半乳糖、半乳糖醛酸和一个未知单糖组成。结论:该法能有效分析单糖组成,方法简单易行。关键词：荨麻;多糖;单糖组成;薄层色谱
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发布时间：2024-09-23 - 摘要：目的:建立家秘枳壳黄连汤中橙皮苷和小檗碱含量的HPLC测定方法。方法:选用Agilent Hypersil C18柱（6mm×250mm,5μm）,流动相:乙腈-0.1%磷酸溶液（28∶72）,检测波长:283nm和350nm,流速:1mL·min-1。结果:橙皮苷线性范围为（0.2051.025）μg,平均加样回收率为100.3%（RSD=1.2%）,小檗碱线性范围为（0.060.42）μg,平均回收率为102.5%（RSD=1.4%）。结论:该实验方法简便易行,结果准确可靠,可用于该制剂的质量控制。关键词：高效液相色谱法;家秘枳壳黄连汤;橙皮苷;小檗碱
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发布时间：2024-09-23 - 摘要：目的:建立健宝灵片中总黄酮的含量测定方法。方法:采用分光光度法。结果:以芦丁为对照品,经显色后,线性范围（0.01260.0630）mg·mL-1,回归方程Y=13.79X+0.0048,r=0.9997,回收率97.05%,RSD为1.22%（n=6）。结论:该法准确、灵敏度高,可作为该制剂的质量控制方法。关键词：健宝灵片;总黄酮;分光光度法
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发布时间：2024-09-23 - 摘要：Objective:By investigating the optimistic configuration of the Anmian Granule to find the optimive prescription for clinic prophase research, and discuss the most effective method of optimise complex prescription of traditional Chinese medicine. Methods:By Using homogeneous-improvement method to evaluate the guideline of pharmacodynamics. And discuss best compatibility and the best dose of the prescription. Results:Dose match group 6 and theoretics group 1 have the best pharmacodynamic action. theoretics group 1 is recommended to explore new medicine because it has more simple configuration. Conclusion:It is fensible to use this method to optimise prescription, because it combines the method of reduce the complex prescription and the method of best dose match.关键词：Anmian Granule;homogenous-improvement;compositive norm;optimized method
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发布时间：2024-09-23 - 摘要：目的:研究番石榴叶挥发油的最佳提取工艺。方法:采用正交实验设计L9（34）,以挥发油提取量为指标,确定最佳提取工艺。结果:番石榴叶粗粉加水8倍量,浸泡2h,提取5h,提取量最高。结论:该工艺为番石榴叶挥发油的最佳提取工艺。关键词：番石榴叶;挥发油;正交设计;工艺
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发布时间：2024-09-23 - 摘要：Objective:To observe the change of CGRP after radiation by 192 Ir irradiation on spinal cord and to detect the protective action of Jingui Shenqi Wan for spinal cord damnification. Method:120 SD rats were randomly divided into four groups: model group, Jingui Shenqi Wan treatment group, prednisone positive group, and normal control group. Rats were given correspondence drug once a day for 14 days （normal control group and model group were given normal saline）. Then Animal models of radiation damage in spinal cord was induced in rats by 192 Ir interstitial irradiation, which was successfully created through the tube inserted in T 11 horizontal place in rat spinal cord by back-fixing technology. The dosage of model group, Jingiu Shenqi Wan treatment group and prednisone positive group was 22 Gy, the normal control group was free of irradiation. CGRP was tested by immunohistochemistry. Result: From the result of immunohistochemistry, we found the number and the brown substance in cells of spinal cord were significantly increased after irradiation. After treated with Jingui Shenqi Wan and prednisone, they were significantly decreased and weaked 8 h, 24 h after brachytherapy（P<0.01）. However,there were no significantly difference compared with the model group 4 week after irradiation. Conclusion: It was found that CGRP regulated and controlled the process of rat spinal damnification. Jingui Shenqi Wan could relive the damnification spinal cord after brachytherapy in rats.关键词：brachytherapy;Jingui Shenqi Wan;CGRP
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发布时间：2024-09-23 - 摘要：Objective:To verify the main pharmacological action of Yiqi Zhuyu granule. Methods:The acute syndrome of blood stasis models of rat were set up by injecting Adr and swimming in ice water in order to observe the hemorheology of rat. The acute myocardial ischemia models of rat were set up by injecting hypophysin. The electrocardiogram was recorded, CK and LDH-L was determined. Using ADP as inductor to measure the degree of platelet aggregation. Results: Yiqi Zhuyu granule could alleviate the damages caused by acute syndrome of blood stasis and acute myocardial ischemia, and it could cut down whole blood viscosity, but there was no significant influence about plasma viscosity. It could cut down the activity of LDH-L, and it could obviously hold back platelet aggregation of rat caused by ADP inductor. Conclusions: Yiqi Zhuyu granule could improve the changes of acute syndrome of blood stasis and alleviate the damages caused by acute myocardial ischemia, and it also could obviously hold back platelet aggregation. All these results prove that it could promoting blood flow.关键词：Yiqi Zhuyu Granule;pharmacodynamics;syndrome of blood stasis;hemorheology;myocardial ischemia
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发布时间：2024-09-23 - 摘要：Objective:To observe the anti-tumor activity of the polysaccharide of Polygonatum cyrtonema Hua in vitro and vivo. Methods: In vitro, the inhibitory effects of polysaccharide on S 180 tissue tumor and MCF-7 were examined by MTT colorimetric assay. The mouse tumor model was used to investigate the effects of polysaccharide on tumor growth. Results: The studies demonstrated that the polysaccharide could inhibit proliferation of S 180 tumor and MCF-7, however, the IC 50 value on the polysaccharide was above 30 μg·mL -1 .It could also increase the spleen index and thymus index in mice. With the dose of polysaccharide changed from low to high, the inhibitory effect of polysaccharide on the growth of S 180 sarcoma-transplanted mice increased gradually, showing an excellent dose-response relation. Conclusions:The polysaccharide of Polygonatum cyrtonema Hua has obvious anti-tumor activity and immunologic functions.关键词：Polygonatum cyrtonema Hua;polysaccharide;MTT method;antitumor
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发布时间：2024-09-23 - 摘要：Objective:To observe the effect of sesamin on myocardial remodeling in renal hypertensive rats. Methods:The model of two kidneys with one clip （2K1C） of renal hypertensive rat was established, the rats were fed to their stomaches daily for 6 weeks with the different dosages of sesamin. LVWI, NO, ET-1 and HYD were measuered and radioimmunoassay was adopted to determine the levels of endothelin-1 （ET-1） in myocardium, immunohistochemistric assay was utilized to observe the expression of nitric oxide synthase （eNOS） protein of myocardium, the ultramicrostructures of myocardium was observed through electron-microscope. Results:Compared with the sham-operated group, the content of LVWI, HYD and ET-1 were obviously increased, vigor of SOD was drastically decreased, the expression of myocardium eNOS protein was distinctly weakened, and it was indicated that disorder of cardiac muscle fiber and hyperplasia of extracellular collagen fiber through the observation of ultramicrostructure in the 2K1C group. High dosage （100 mg·kg -1 ） sesamin tangibly ameliorated the pathologic changes such as disorder of cardiac muscle fiber,hyperplasia of extracellular collagen fiber and LVWI,and the content of HYD and ET-1 were obviously decreased, vigor of SOD was drastically increased, the expression of myocardium eNOS protein was clearly increased. Conclusion:The results showed that sesamin has an effect of against myocardial remodeling, its mechanisms were probably mediated through increasing the content of NO, inducing the expression of eNOS protein, decreasing the content of ET-1 and so on.关键词：sesamin;myocardial remodeling;endodermis nitric oxide synthase;nitric oxide;endothelin-1
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发布时间：2024-09-23 - 摘要：Objective:To study the effect of Tongmai（TMG） on experimental myocardial ischemia. Methods: By ranine vein injection pituitary creates rats myocardial ischemia（0.5 U·kg -1 ）,to observe the effect of TMG on the J points’ change in rats ECG.; Choose the acute myocardial damage model in rats induced by Iso, to observe the J points’change in rats ECG. and the effect on lipid peroxidation after injecting Iso（sc 8 mg·kg -1 ）; 0.8 mg·kg -1 adrenalin was administrated by subcutaneous injection to establish rat blood stasis model; the formation of thrombus in vitro and the tolerance experiment of mouse under normal pressure. Results: TMG（9、4.5、2.3 g·kg -1 ） remarkably restrained the change of J point in rat’s ECG after the injection of Pit,and obviously inhibited the state of J points’ descent in rats myocardial ischemia induced by Isoprenaline, reduce the level of MDA, advance the level of SOD; could inhibit the formation of thrombus in vitro; could reduce the blood viscosity in blood stasis model. TMG also can prolong the mouse’s survival time in hypoxia. Conclusions: TMG has protective action on acute experimental myocardial anoxia,and the effect is related to improve the hemorheology, inhibit the lipid peroxidation and the formation of thrombus, degrade oxygen consumption in cardiac muscle.关键词：Tongmai;myocardial ischemia;pituitary;isoprenaline;lipid peroxidation;hemorheology
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发布时间：2024-09-23 - 摘要：Objective:To investigate the effect of traditional chinese medicine Yikunning on the expression of vascular endothelial growth factor （VEGF） in rat ovaries during perimenopause period. Methods:The animal model of perimenopause rats was established by unforced aging.30 female Wistar rats of 12 months old were randomly divided into three groups:old controls,western medicine controls,chinese medicine experimental group.10 female rats of 5 months old served as young controls.The animals were given with corresponding drugs for 4 weeks. The site-specific expression of VEGF in ovaries of rats was detected by immunohistochemistry; the quantitative expression of VEGF in ovaries of rats was detected by Western Blot;the quantitative expression of VEGF mRNA in ovaries of rats were detected by RT-PCR. Results:Compared with young controls,the expressions of VEGF mRNA in ovaries of old controls increased significantly,while the expressions of VEGF in ovaries of chinese medicine experimental group decreased significantly.The expression of VEGF164 mRNA and VEGF120 mRNA of the young controls,chinese medicine experimental group and western medicine controls were lower than the expression of VEGF mRNA of old controls（P<0.05）,which were consistent with the result of the expression of VEGF. Conclusions: Yikunning could down-regulate the expression of VEGF mRNA and protein in rat ovaries during perimenopause period,which may be one of the mechanisms of Yikunning to treat perimenopausal syndrome.关键词：Yikunning;VEGF;perimenopause period;ovary;rat
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发布时间：2024-09-23 - 摘要：Objective:To investigate the effect of Qingyi Huaji（QYHJ） Formula on serum immunosuppressive factors and proliferation activity of splenic lymphocytes of mice with pancreatic cancer Panc 02. Methods: The mice were randomly divided into NS group,interleukin-2（IL-2） group and QYHJ groups at low,medium and high dosages. After treatment, tumor growth was evaluated, the levels of serum immunosuppressive factors such as soluble interleukin-2 receptor（sIL-2R）,transforming growth factor β1（TGF-β1） and vascular endothelial growth factor（VEGF） were measured by ELISA, the proliferation activity of splenic lymphocytes cell were measured by CCK-8 colorimetry. Results: The tumors in all QYHJ groups were lighter than in NS group（P<0.05）,the levels of serum sIL-2R,TGF-β1 and VEGF in all QYHJ groups were lower than in NS group, when the proliferation activity of splenic lymphocytes in all QYHJ groups was higher than in NS group（P<0.05）.Conclusion: QYHJ Formula may inhibit the proliferation of pancreatic cancer in vivo, in addition it may inhibit the secretion of immunosuppressive factors and enhance lymphocytes’ immune function so as to improve the immunosuppressive state of the host.关键词：Qingyi Huaji Formula;pancreatic cancer;immunosuppressive factor;splenic lymphocyte
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发布时间：2024-09-23 - 摘要：目的:研究速效心痛滴丸调理血脂、改善血液流变性及抗动脉粥样硬化的作用特点。方法:用高脂饲料喂养家兔8周复制实验性动脉粥样硬化模型;模型家兔分别灌胃速效心痛滴丸54mg·kg-1,108mg·kg-1,216mg.kg-1和阳性对照药（速效救心丸64mg·kg-1）,模型组和空白组灌胃等量0.5%羧甲基纤维素钠（0.5%CMC-Na）,每日1次,共治疗给药4周。采用酶法检测家兔血清TC,TG和HDL;血液黏度计测定全血和血浆黏度;离心法测红细胞压积;图像分析仪测主动脉斑块面积。结果:速效心痛滴丸各剂量组均能降低TC,TG和LDL水平,且作用优于速效救心丸组;速效心痛滴丸（216mg·kg-1）可明显提高HDL水平;速效心痛滴丸各给药组均能降低全血和血浆黏度、红细胞压积、减轻主动脉斑块面积,与速效救心丸组比较,速效心痛滴丸（216mg·kg-1）缩小主动脉斑块面积的作用更明显。结论:速效心痛滴丸对实验性动脉粥样硬化家兔的血脂水平、血液流变性和主动脉斑块形成均有不同程度的改善作用,在降低TC,TG,LDL水平和缩小主动脉斑块面积方面的作用较速效救心丸更显著。关键词：速效心痛滴丸;动脉粥样硬化;血脂;脂蛋白;血液流变学;主动脉斑块面积
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发布时间：2024-09-23 - 摘要：Objective:By comparing the content of total flavones and chlorogenic acid and antibacterial activity between the artificial tetraploid and the wild plant of herba Taraxaci,it is aimed at providing the theoretical support for the tetraploid plant of herba Taraxaci application. Methods: The content of total flavones and chlorogenic acid was detected by ultraviolet spectrophotometry. Inhibitive effects about water-abstract by K-B scattering methods towards the Staphylococcus aureus,Escherichia coli,Bacillus aeruginosus,Bacillus paratyphosus were evaluated. Results: Tetraploid plant showed higher level of flavonoid and chlorogenic acid than those of the wild plant. The tetraploid and the wild plant of herba Taraxaci had satisfactory antibacterial activity on four kinds of bacteria. Conclusion: The tetraploid plant of herba Taraxaci would be useful to take the place of medicine herba Taraxaci.关键词：tetraploid plant of herba Taraxaci;total flavones;chlorogenic acid;in-vitro antibacterial activity
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发布时间：2024-09-23 - 摘要：Objective:To observe the effects of baicalin in chronic alcoholic live injury rats,and to study the terapeutic effects and mechanisms of baicalin on alcoholic live injury rats. Methods:The rats were given 56°（v/v） alcohol 5 mL·kg -1 twice daily for 28 days by ig,from the 5 th week once daily for 4 weeks.In the same time the rats were given test agents according to the protocol for 28 days. Results: The experiments indicated that baicalin could obviously degraded the content of ALT,AST,MDA in rats’serum and liver and increased the activity of SOD and GSH-Px. It also reduced the content of TNF-α in serum. Conclusions: Baicalin has obvious protective effect to alcoholic liver injury in rats. Down regulation of TNF-α and MDA might be involved in the mechanism.关键词：baicalin;alcoholic liver injury;anti-oxidation;tumor necrosis factor（TNF-α）
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发布时间：2024-09-23 - 摘要：Objective:To observe the influence of the cute soft tissue injury disease. Methods: Laosun Kangfu Tablets were given 3.0,10.0,30.0 g·kg -1 （mice） or 2.2,7.5,22.0 g·kg -1 （rats） daily by oral administration for 7 days. Analgesia was tested by scald-plate caused sole-ache, actic acid caused belly-ache. The anti-inflammtory was tested by auricle swelling and carrageenan caused foot-swelling. The Resistance to acute soft tissue injury was tested by damages caused by freely falling mass damages models. Results:The results showed that there were significant differences between the treatment groups and the control groups（P<0.05）. Laosun Kangfu Tablets have obvious analgesia, anti-inflammtory, resisting the acute soft tissue injury. Conclusions: Laosun Kangfu Tablet is effective for the treatment of acute soft tissue injury.关键词：Laosun Kangfu Tablet;acute soft tissue injury;analgesia;anti-inflammation
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发布时间：2024-09-23 - 摘要：目的:观察护肝片预防小鼠酒精性肝损伤的效果。方法:采用乙醇灌胃致小鼠酒精性肝损伤模型,观察护肝片40,400,1200mg·kg-1ig32d后小鼠病理组织学改变及肝组织中丙二醛（MDA）、还原型谷胱甘肽（GSH）和甘油三酯（TG）含量的变化。结果:与模型组比较护肝片高剂量组肝细胞脂肪变性指数、MDA含量显著降低（P<0.05）,TG含量明显降低（P<0.01）;低、高剂量组GSH含量明显升高（P<0.01）。结论:护肝片具有预防小鼠酒精性肝损伤的作用。关键词：护肝片;酒精性肝损伤;小鼠
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发布时间：2024-09-23 - 摘要：目的:研究化湿消脂口服液对大鼠营养性肥胖症的减肥降脂作用。方法:选用刚离乳健康SD大鼠50只,随机分成5组,分别为（饲基础饲料）对照组、（饲营养饲料）模型组和化湿消脂口服液预防性治疗组（分别为13,6.5,3.253个剂量组）。测定给药45d后大鼠体重、尾长、Lees指数、生殖腺周围脂肪组织的重量和脂肪细胞数以及血清总胆固醇（TC）、甘油三酯（TG）。结果:正常对照组和预防性治疗组与模型组相比大鼠的体重、Lees指数、生殖腺周围脂肪组织重量、血清TC和TG均有显著性降低（P<0.05、P<0.01）、相同面积中脂肪细胞数目明显增加（P<0.01）。结论:化湿消脂口服液对大鼠营养性肥胖症有减肥降脂作用。关键词：化湿消脂口服液;大鼠营养性肥胖症;总胆固醇;甘油三酯
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- 54
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发布时间：2024-09-23 - 摘要：目的:观察运用加味玉屏风合剂预防治疗中老年反复呼吸道感染的临床疗效。方法:加味玉屏风合剂,随机设玉屏风合剂治疗组130例,西药丙种球蛋白治疗对照组86例。10d为1疗程,连用3个疗程。结果:两组治疗后加味玉屏风合剂总有效率98.5%,对照组总有效率为89.5%,经统计学处理P<0.05,差异具有显著性意义。结论:加味玉屏风合剂治疗中老年反复呼吸道感染疗效肯定。关键词：呼吸道感染;玉屏风合剂;中老年
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- 58
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发布时间：2024-09-23 - 摘要：目的:探讨活血镇痛汤配合硬膜外患者自控镇痛（PCEA）预防下肢骨科术后深静脉血栓（DVT）形成的临床疗效。方法:中药组59例以活血镇痛汤口服,术后行PCEA镇痛;对照组58例口服肠溶阿司匹林并配合低分子右旋糖酐静脉滴注,术后行PCEA镇痛。比较两组患者DVT发生率及治疗前后血液流变学及凝血指标变化的差异。结果:①DVT的发生率中药组为6.78%,对照组为18.97%,两者比较（P<0.05）。②中药组血液流变学及凝血指标术后2d分别与术前相比较（P<0.01）,与对照组术后2d比较（P<0.05）。结论:活血镇痛汤配合PCEA在预防下肢骨科术后DVT发生方面有可靠的效果及良好的安全性。关键词：深静脉血栓;活血镇痛汤;硬膜外患者自控镇痛
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发布时间：2024-09-23 - 摘要：Six monomers including ligustilide,imperatorin,ferulic acid,osthole,3-n-butylphthalide and praeruptorin C are the active components of main pungent herbs in Umbelliferae. Through the review, showed that six monomers all have the activity of vasodilation,deduced that six monomers have certain relevance with pungent herbs of Umbelliferae.关键词：Umbelliferae;vasoactive;chemical constituents;theory of drug property
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- 243
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发布时间：2024-09-23 - 摘要：Objective:We sought to summarize frequently effective traditional Chinese drug and prescription for Ulcerative Colitis （UC） as well as to sum up clinical classification and regularity of compatibility though analysis of clinical data. Methods: Prescriptions for oral use were searched and screened from acquired papers. Cluster analysis was used to explored frequently effective traditional Chinese drug,prescription and regularity of compatibility. Conclusion: The main pathogenesis of UC is spleen-asthenia with excessive damp,cold-heat complex. The foundational prescription is Black plum pill uniting Decoction of Four Mild Drugs.关键词：ulcerative colitis;cluster analysis;therapy
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发布时间：2024-09-23 -
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