最新刊期
      卷 ， 期 10 ， 2006
      • Issue 10, Pages: 1-2(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.001
        摘要：目的:黑布药膏剂型改革的研究。方法:通过透皮吸收实验,HPLC法确立累积透皮量与时间的关系（透皮吸收速率）。结果:没食子酸在0.11.1μg范围内现性关系良好,新剂型中未超微粉涂膜剂透皮吸收速率是29.012 9,黑布药膏透皮吸收速率是26.911 6,超微粉涂膜剂透皮吸收速率是20.2763。结论:新剂型中未超微粉涂膜剂透皮吸收速率最大,其次是黑布药膏,而超微粉的涂膜剂透皮吸收率最低,从而为进一步研究提供了实验依据。  
        关键词：黑布药膏;涂膜剂;高效液相色谱法;透皮吸收   
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        发布时间：2024-09-23
      • Issue 10, Pages: 3-4(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.002
        摘要：目的:制定麻杏石甘配方颗粒质量标准。方法:采用薄层色谱法鉴别麻黄和甘草,高效液相色谱法测定麻黄碱的含量。结果:薄层色谱斑点清晰,分离度好,含量测定平均回收率为98.7%。结论:方法简便,准确,可供本品质量控制。  
        关键词：高效液相色谱法;薄层色谱法;麻黄碱;麻杏石甘配方颗粒   
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      • Issue 10, Pages: 5-7(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.003
        摘要：目的:为青皮贮藏条件要求及质量评价标准提供科学依据。方法:利用HPLC方法测定青皮中橙皮苷含量,观察1年内橙皮苷、浸出物等含量变化。Kromasil C18色谱柱（4.6mm×250mm,5μm）,检测波长284nm,流动相甲醇-水-冰醋酸（35∶61∶2）,流速1.0mL.min-1,柱温35℃。结果:储藏1年内,饮片外观、成分基本稳定。  
        关键词：青皮;储藏期;湿度环境;橙皮苷   
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        发布时间：2024-09-23
      • Vol. 0, Issue 10, Pages: 7-18(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.004
          
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      • Issue 10, Pages: 8-9(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.005
        摘要：目的:研究枳实配方颗粒的HPLC特征图谱,为控制和评价质量提供依据。方法:采用Zobax Eclipse XDB-C18色谱柱,乙腈-水-磷酸-十二烷基硫酸钠（20∶80∶0.1∶0.2）为流动相,检测波长为275nm。结果:建立了枳实配方颗粒的HPLC特征图谱分析方法。结论:实验结果表明该方法灵敏性高,重复性好。  
        关键词：枳实配方颗粒;高效液相色谱;特征图谱;辛弗林   
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        发布时间：2024-09-23
      • YANG Lan~,WANG Man-yuan,ZHANG Dong,TU You-you
        Issue 10, Pages: 10-11(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.006
        摘要：Objective:To develop a method for the determination of scopoletin in Qinghao.Method:Sample was extracted with methanol.Scopoletin in Qinghao was determined by HPLC with ODS column.The mobile phase was methanol-0.08% H3PO4（4∶6）solution.The detection wavelength was 340nm.Result:Scopoletin in sample solution was well separated.Linearity of scopoletin was good（r=（0.999 9））in range of 0.021～0.42μg.The average recovery was 99.3%,RSD was 2.0%.Conclusion:The method is simple,accurate,repeatable and suitable for the determination of scopoletin in Qinghao.  
        关键词：HPLC;Qinghao;Scopoletin;determination   
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        发布时间：2024-09-23
      • Issue 10, Pages: 12-13(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.007
        摘要：目的:采用高效液相色谱法测定人参健脾片中柚皮苷的含量。方法:采用Kromasil C18色谱柱（250mm×4.6mm,5μm）,流动相:乙腈-1%冰醋酸水溶液（19∶81）;流速:1.0mL.min-1,检测波长为:283nm。结果:柚皮苷线性范围为0.1961.764μg,平均回收率为99.03%,RSD=1.08%（n=6）,测得3批样品中柚皮苷的含量分别为0.75,0.72,0.76mg/片。结论:所建方法简便、准确、重复性好,可用于人参健脾片的质量控制。  
        关键词：人参健脾片;柚皮苷:高效液相色谱   
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        发布时间：2024-09-23
      • Issue 10, Pages: 14-15(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.008
        摘要：目的:制订秘制橘红痰咳胶囊的薄层色谱鉴别与含量测定方法。方法:采用薄层色谱法鉴别柚皮苷,贝母素甲、乙,白前,高效液相色谱法测定化橘红中柚皮苷的含量。结果:薄层色谱斑点清晰,重复性好。柚皮苷在0.161 20.806 0μg范围内线性关系良好,平均回收率为98.8%,RSD为0.8%。结论:该方法简便易行,重复性好。  
        关键词：蜜制橘红痰咳胶囊;薄层色谱;高效液相色谱;柚皮苷   
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        发布时间：2024-09-23
      • LIU Ji-jin~,HUANG Fu-xi,XIONG Ying
        Issue 10, Pages: 16-18(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.009
        摘要：Objective:To develop a Capillary GC method to determine the seven components,α-pinene,eucalyptol,camphor,menthol,methyl salicylate,cinnamia aldehyde and eucalyptal in Huoluo oil.Method:A fused silica capillary column was used.The intial temperature of column was kept at 90℃ for 1 min,then raised to 180℃ at the rate of 6℃·min-1,finally to 250℃ at the rate of 25℃·min-1 and maintained the temperature for 5 min,the carry gas was nitrogen.The injector and detector temperature was 220℃ and 260℃.Injections were performed in the splitless mode and an FID was used as the detector.Results:The standards curves of α-pinene,eucalyptol,camphor,menthol,methyl salicylate,cinnamia aldehyde,eucalyptal are linear within the range of 6.94～41.64μg·mL-1,1.00～6.01 μg·mL-1,6.86～41.1 μg·mL-1,24.1～144.5 μg·mL-1,24.09～144.55μg·mL-1,24.16～144.98μg·mL-1,1.03～6.17μg·mL-1,1.04～6.25μg·mL-1,and RSD was 1.8,1.1,0.9,0.7,1.1,1.7,1.1%.Conclusion:This method is simple and accurate,and can be used to control of Huoluo oil.  
        关键词：Huoluo oil;camphor;Menthol;methyl salicylate;Cinnamia aldehyde;Eucalyptal;Assay;capillary GC   
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        发布时间：2024-09-23
      • Issue 10, Pages: 19-20(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.010
        摘要：目的:应用高效液相色谱法测定小儿咳喘灵颗粒中绿原酸的含量。方法:采用Shim-pack-C18柱（5μm,4.6mm×150mm）,乙腈0.4%磷酸水溶液（11∶89）为流动相,检测波长327nm。结果:线性范围为0.21761.088μg,r=0.999 4,回收率为98.23%,RSD为0.97%。结论:该方法用于测定小儿咳喘灵颗粒中绿原酸的含量具有操作简便、结果准确、灵敏的特点,可用于该制剂的质量控制。  
        关键词：高效液相色谱法;绿原酸;小儿咳喘灵颗粒   
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        发布时间：2024-09-23
      • Vol. 0, Issue 10, Pages: 20-65(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.011
          
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      • Issue 10, Pages: 21-22(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.012
        摘要：目的:建立苍术组培苗挥发油中β-桉叶醇的含量测定方法。方法:用水溶液提取,采用GC内标法测定β-桉叶醇的含量。结果:β-桉叶醇进样量在500175 0ng范围内线性关系良好,工作曲线为Y=0.875 4X+0.101 3,r=0.999 6。平均回收率为105.2%,RSD为3.62%。（n=5）。结论:建立的方法可用于苍术组培苗、愈伤组织等挥发油中β-桉叶醇的含量。  
        关键词：气相色谱;正十六醇;苍术组培苗;β-桉叶醇   
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        发布时间：2024-09-23
      • ZHAO Bao-sheng,HUO Hai-ru~,LI Lan-fang,MA Yue-ying,GUO Jian-you,HE Xi-rong,JIANG Ting-liang
        Issue 10, Pages: 23-25(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.013
        摘要：Objective:To investigate the influence of Guizhi Tang to secreting inflammatory factors in RAW264.7.Methods:RAW264.7 cell line was stimulated by Lipopolysaccharide and treated with the serum of containing Guizhi Tang at the same time.24 hours later,collected the supernatant and measured the inflammatory factors such as NO、TNF-α and IFN-β.Results:Guizhi Tang can decrease the amount of NO、TNF-α and IFN-β,and shows dose-dependent relationship significantly.Conclusion:Guizhi Tang may produce the anti-inflammatory effect by decreasing the amount of NO、TNF-α and IFN-β.  
        关键词：guizhi tang;Drug Serum;macrophage;NO;TNF-α;IFN-β   
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        发布时间：2024-09-23
      • LONG Yin,LIU Jia-yun,LIU Li,WANG Zong-ren~
        Issue 10, Pages: 26-28(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.014
        摘要：Objective:To increase the diversity of hirudin-shuffled libraries by DNA family shuffling method.Methods: PCR products of HV1,HV2 and HV3 genes were combined and digested with DNase Ⅰ.Then random fragments about 50bp were purified and reassembled to the same size of hirudin genes by two amplifications of PCR with or without primers. Pools of hirudin mutant genes were ligated into phagemid pCANTAB-5E vector and three randomly picked clones were sequenced to observe the efficiency of shuffling.Results: The hirudin-shuffled libraries contained 1.2×106 different clones and the three clones were hybrids of three parent genes.Conclusion:These results show that a highly shuffled library of hirudin genes has been obtained which lay a substantial foundation for screening hirudin molecules with high bioactivity.  
        关键词：hirudin;DNA shuffling;genes   
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        发布时间：2024-09-23
      • XIONG Yu-lan~1,WANG Yan-li~1,SUN Jian-hui~1,WEI Tai-ming~2,YAN Yu-ning~2,ZHANG Si-ju~1,ZHOU Zhong-ming~1
        Issue 10, Pages: 29-31(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.015
        摘要：Objective:To observe the influence of sedum sarmentosum tricin-glucoside on proliferation of spleen T and B lymphocytes of normal mice.Methods:Method of mixturing（）3H-TdR to mice spteen cell was applied.After stimulation with canavaline（ConA）or lipid polysaccharides（LPS）,the radioactive relative quantity（cpm） of（）3H-TdR in DNA in spleen cell.Results:The dosages in 100,10,1μg/mL（final concentration）of sedum sarmentosum tricin-ghcoside had highly significant inhibition to cpm number of T lymphocyte（P<0.001）;the dosage in 100μg/mL of sedum sarmentosum tricin-glucoside had highly significant inhibition to cpm number of B lymphocyte （P<0.01）.Conchsions:Sedum sarmentosum tricin-glucoside can obviously inhibit proliferation of spleen T and B lymphocytes of normal mice.  
          
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        发布时间：2024-09-23
      • WANG Hong-hai,XIE Ming~
        Issue 10, Pages: 31-35(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.016
        摘要：Objective:To observe gastroenteric hormones content changes of blood in model rat of spleen-qi deficiency during different modelling time points.Methods:Adopting excess fatigue（by swimming） and out of constant diet on rats for constant three weeks and stopping doing on them in the 4w.Results:Compared with the control group,the model rats distinctly appear diet reduction,feces rarefaction,reduction activities,accidie and extrados,etc in modelling 2～3w;weight significantly failed,and it has yet to come back in the 4w;urine D-xylose excretion rate significantly falled during 2～4w;GAS and MTL level of serum failed in the 3w and significantly came back during natural recovery period;SS level markedly lower in the 1w,and no significant changes in the remaining time points;VIP level markedly rised in the 2w,and significantly failed in 3w;SP level clearly failed in the 3w;NPY level clearly lower in the 2～3w,and β-EP level clearly declined in the 4w.Conclusion:The model rat made by excess fatigue and out of constant diet for constant three weeks can appear diet reduction,feces rarefaction,reduction activities,etc;and abnormal changes of weight,urine D-xylose excretion rate,and gastroenteric hormones of Blood.  
        关键词：syndrome of spleen-qi deficiency;animal model;gastroenteric hormones   
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        发布时间：2024-09-23
      • CAO Ying,LIANG Ri-xin~,YANG Bin,WANG Lan,YANG Qing,WANG Yan-li
        Issue 10, Pages: 36-38(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.017
        摘要：Objective:To observe the protective effect of（-）-Catechin gallate and（+）-Epicatechin on Xanthine-Xanthine Oxidase System injury in cultured cardiomyocytes.Methods:The injury model of cultured neonatal rat cardiomyocytes was induced by Xanthine-Xanthine Oxidase System.Cell proliferation was detected by MTT assay,lactate dehydrogenase（LDH） activity,Maleic Dialdehyde（MDA） and Superoxide Dismutase（SOD） level in supernatant were measured with colorimetric assay.Results:Compared with model group,（-）-CG,（+）-EC can obviously increase survival rate of cardiomyocytes,decrease LDH activity and MDA level,increase SOD level in supernatant.Conclusion:（-）-CG、（+）-EC can protect cultured cardiomyocytes against Xanthine-Xanthine Oxidase System damage.  
          
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      • Issue 10, Pages: 39-40(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.018
        摘要：目的:制备大鼠慢性阻塞性肺疾病（COPD）模型,观察参七虫草胶囊对其内皮素和一氧化氮水平的影响。方法:采用烟熏加脂多糖气管滴入制作大鼠COPD模型,给与参七虫草胶囊,观察各组大鼠内皮素和一氧化氮水平的变化。结果:模型组的血清、肺组织及肺泡灌洗液（BALF）中内皮素（ET-1）含量与空白对照组比较均有明显升高,其一氧化氮（NO）水平则明显降低,提示慢阻肺存在ET-1/NO失衡,而参七虫草胶囊可调节其失衡。结论:参七虫草胶囊能改善COPD模型大鼠ET-1/NO失衡。  
        关键词：参七虫草胶囊;慢性阻塞性肺疾病;内皮素;一氧化氮   
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      • CHEN Yun-hua~
        Issue 10, Pages: 41-43(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.019
        摘要：Objective:The effects of Danggui Buxue Tang（Chinese Angelica decoction for replenishing blood;DBT） on the erythrocyte functions were studied in the acute hypoxia mice.Methods:The mice were divided into five groups:control,model,and DBT with three dosages（20,10,5g/kg·d）.Water or DBT were administrated for 10 days.Acute hypoxia model was made by putting the mice into hermetical specimen bottles for 10 minutes.Then the erythrocyte membrane fluidity,the erythrocyte deformability and the erythrocyte immunity was tested.Results:DBT（5g/kg·d） could prevent the erythrocyte membrane fluidity from decreasing.The same actions were observed for the erythrocyte deformability and the erythrocyte immunity function in the acute hypoxia mice.DBT 10g/kg·d could prevent the erythrocyte membrane fluidity and the erythrocyte deformability from decreasing.However,effects were not observed with DBT 20g/kg.Conclusion:The above study shows that small and middle dose DBT can improve the function of red blood cell,which may be the mechanism of invigorating qi to promote blood of DBT.  
        关键词：Danggui Buxue Tang;erythrocyte membrane fluidity;erythrocyte deformability;erythrocyte immunity;hypoxia   
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        发布时间：2024-09-23
      • YANG Ming~1,FU Ping~1,CHEN Ying-li~1,WANG Qing~1,WANG Yue-zhen~2,LI Wei~1
        Issue 10, Pages: 44-46(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.020
        摘要：Objective:To discuss the mechanism of "Xiao Geng Yan Jing" capsule for treating menopausal syndrome.Methods:Extirpation of ovaries of rats was cartied out.After 30 days of oral administration,serum was collected to determine the contents of estradiol（E2）、luteinizing hormone（LH）、follicle-stimulation hormone（FSH）,The contents of 5-hydroxytryptamine（5-HT）、norepinephrine（NE）、dopamine（DA） and 5-hydroxyindoleacetic acid（5-HIAA） in brain was determined.The uterus was weighed.Results:The experiment showed that "Xiao Geng Yan Jing" capsule could decrease the levels of FSH and LH obviously,and increase the level of E2.For the brain of castrated rats,it could decrease 5-HT、5-HIAA contents and 5-HT/NE.But for NE、DA contents and 5-HIAA/5-HT it have no influence.Moreover,this medicine can increase the weight of the castrated rat and their uterus.Conclusion:"Xiao Geng Yah Jing" capsule can improve and treat menopausal syndrome though the mechanism of adjusting sexual gland and nervous function.  
        关键词：Xiaogengyanjing capsule;sexual hormone;ovary   
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        发布时间：2024-09-23
      • ZHOU Shan-ni,WANG Qiu-juan~
        Issue 10, Pages: 47-50(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.021
        摘要：Objective:To research the protective effect and mechanism of FBD on cerebral ischemia reperfusion.Methods:Rat model of cerebral ischemia was established by applying middle cerebral artery occlusion（MCAO）.Effect of FBD on cerebral functions,infarction percentage,water-contained percentage,biochemical indices and histology of the rat brains after MCAO were in vestigated.Effect of FBD on the blood brain barrier permeability of mice after cerebral ischemia reperfusion were also investigated.Results:FBD can obviously decrease the cerebral function score,cerebral infarct size and water content,improve the activities of Na+-K+-ATPase and Ca2+-ATPase.reduce the content of MDA and NO of rat brains（P<0.05～0.01）,repair pathological injury of ischemia-reperfusion rat.FBD can remarkably decrease blood brain barrier permeability of mice after cerebral ischemia reperfusion（P<0.05）.Conclusion:FBD has good effects on cerebral ischemia reperfusion.  
        关键词：Optimized Danggui Shaoyao San（FBD）;cerebral ischemia reperfusion;middle cerebral artery occlusion（MCAO）;blood brain barrier   
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        发布时间：2024-09-23
      • SONG Chong-shun~,REN Ying,YIN Jun-xiang,LI Ben-zhi,SUN Hai-yun,CUI Jie-feng,GUO Jing,DAI Xin,YANG Jin-duo,TAN Wei
        Issue 10, Pages: 51-53(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.022
        摘要：Objective:To study the preventive and therapeutic effect of Chinese medicine Jiaweibiejiajian Pill（JWBJ）on rats with hepatic fibrosis induced by human serum albumin.Methods:The rats model with hepatic fibrosis was induced by multiple subcutaneous injections of serum albumin solution for 4 times.After it was confirmed that there were albumin antibody in rats serum,and then rats were divided into model-group,low-dose group of JWBJ,mediate-dose group of JWBJ and high-dose group of JWBJ.Rats were given JWBJ orally every day,and injected albumin solution into the rats caudal veins for 9 times during 4 weeks.When hepatic fibrosis was verified to come into being by pathological examination.Alanine amino transaminase（ALT）,aspartate aminotranferase（AST）,total protein（TP）,albumin（ALB） Hyaluronic acid（HA）,Laminin（LN）,Collagen Type（PC） in serum of all rats were examined.Results:Compared with the model group,JWBJ could obviously decrease the concentration of serum ALT,AST,HA,LN,CIV and increase the concentration of serum ALB,TP,and increase the ratio of serum A/G of rats with hepatic fibrosis,and reduce the degree of hepatic fibrosis.Conclusion:JWBJ can effectively prevent and treat hepatic fibrosis induced by serum albumin.  
        关键词：Jiaweibiejia pill;animal models of hepatic fibrosis;albumin   
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        发布时间：2024-09-23
      • Issue 10, Pages: 54-55(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.023
        摘要：目的:观察静心口服液对12月龄雌性大鼠内分泌功能的影响。方法:选用12月龄（中年）雌性大鼠,切除双侧卵巢,造成“更年期”模型,灌服静心口服液21d,测定其子宫重量,观察大鼠阴道上皮细胞的变化和用放射免疫法测大鼠的促卵泡激素（FSH）、促甲状腺激素（TSH）含量并测定大鼠血清雌二醇（E2）的含量。结果:静心口服液能显著增加12月龄去势雌性大鼠子宫的重量,能显著降低其血清FSH和TSH的含量,增加其动情期的发生率,能显著增加雌性大鼠血清E2含量。结论:静心口服液对中年雌性去势大鼠具有调节内分泌功能的作用。  
        关键词：静心口服液;去势;内分泌功能;大鼠   
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      • SHI Hai-bo~,MIAO Yan-bo,WANG Li-ping,WANG Wei
        Issue 10, Pages: 56-57(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.024
        摘要：Objective:To investigate the effects of Tiaozhiqinggan（TZQG） capsule on experimental hyperlipidemia in rats and fatty liver in mice.Methods:The rat hyperlipidemic model was induced by feeding caloric diet and mouse fatty liver model was induced by ethionine,and effect of different doses of TZQG capsule on reducing blood lipid and prevention of fatty liver was obsevered.Results:TZQG capsule evidently lowered the levels of CHO,TG,and LDL-C,increased the HDLC,elevated the ratio of HDL-C and CHO in blood,and decreased the liver weight and abdominal fat of hyperlipidemic rats.It significantly improved the transformation of fatty liver of model mice.Conclusion:TZQG capsule had markedly effects on reducing blood lipid and prevention of fatty liver.  
        关键词：Tiaozhiqinggan Capsule;hyperlipidemia;Fatty liver   
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        发布时间：2024-09-23
      • WANG Di-sheng~
        Issue 10, Pages: 58-60(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.025
        摘要：Objective:To investigate the protective effects of Gankang on D-galactosamine-induced liver injury and study its possible mechanism.Methods:The model of chemical injury in liver of mouse was prepared.The level of alanine aminotransferase（ALT）,aspartate aminotransferase（AST） in serum,malondiadehyde（MDA）content,nitric oxide（NO）in liver homogenate were assayed by spectrophotometer.Results:Gankang(200,400,800mg·kg-1)significantly decreased the levels of serum transaminase（ALT,AST）,liver index and spleen index.Furthermore,Gankang also decreased MDA and NO level in liver homogenate.Conclusion:Gankang possesses protective action on chemical injury in liver of mice,which is related to its mechanism of ressistance to the liver cell oxidation.  
        关键词：Gankang;Chemical liver injury;D-GaiN   
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      • FAN Ying~
        Issue 10, Pages: 61-65(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.026
        摘要：Objective:Through analyzing the origin and evolution and understanding the compatible content of Angelica Decoction for Tonifying Blood,discovering the inherent relation among the compatibility,function and disease,inner laws for differentiation syndrome in principle for formula compatibility will be explored.Methods:We discussed the links between the compatibility of Angelica Decoction for Tonifying Blood and the disease that this decoction can treat by researching the ancient and modern literature.Results:Though the different cognitions about the effect of this decoction by doctors in different era exist,the pathogeny of the disease that Angelica Decoction for Tonifying Blood can treat is blood deficiency.We find that the emphasis of Tonifying Blood in this decoction is different because of the compatible difference according to the modern medicine research.Conclusion:The function stress of Angelica Decoction is tonifying blood."Blood deficiency"consists in pathologic change of the disease which this decoction can cure continually.  
        关键词：Angelica Decoction for Tonifying Blood;origin and evolution;compatibility;function   
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        发布时间：2024-09-23
      • HU Hong-tao,CHENG Ze-xiong~
        Issue 10, Pages: 66-69(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.027
        摘要：Objective:To introduce the advance of the Chinese medicine combined with Lamivudine in the treatment of chronic hepatitis B in the recent years.Methods:The literatures on the Chinese medicine in the treatment of chronic hepatitis B was Summarized.Results:Chinese medicine is effective in treating chronic hepatitis B,especially combined with Lamivudine.Conclusion:Chinese medicine with Lamivudine is effective in the treatment of chronic hepatitis B.its mechanisms are to be further investigated.  
        关键词：Chinese medicine;lamivudine;chronic hepatitis B;advance   
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      • CHENG Long~
        Issue 10, Pages: 70-71(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.028
        摘要：The current evaluations on clinical safety of traditional Chinese medicine can not fully reflect the information of drug safety due to various reasons or shortcomings.Based on a comprehensive evaluation of the existing clinical trails,we try to define the neglected factors and to improve the methods for safety evaluation.The efforts will provide the foundation for the future safety evaluation of clinical trails for traditional Chinese medicine.  
        关键词：Evaluation of safety;Clinical trails;adverse reaction   
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        发布时间：2024-09-23
      • Vol. 0, Issue 10, Pages: 72(2006) DOI: 10.13422/j.cnki.syfjx.2006.10.029
          
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        发布时间：2024-09-23
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